Can Starvation Cause Metabolic Acidosis?

Share on facebook

Severe Acidosis Caused By Starvation And Stress.

Severe acidosis caused by starvation and stress. Department of Pediatrics, Children's Hospital of Wisconsin, Milwauke, WI, USA. A 1-year-old boy had severe anoxic brain injury owing to a cardiorespiratory arrest. He had an initial metabolic acidosis, but this largely resolved by hospital day 2. He then had a persistent, profound metabolic acidosis. Evaluation on hospital day 6 found that the patient had ketonemia, ketonuria, and a normal serum glucose level; he had received no intravenous dextrose during his hospitalization. The dextrose-free fluids were given initially to protect his brain from the deleterious effects of hyperglycemia after brain injury. Continuation beyond 24 hours was inadvertent. The initiation of dextrose-containing intravenous fluids produced a rapid resolution of his metabolic acidosis. Starvation usually produces a mild metabolic acidosis, but when combined with physiologic stress, starvation may cause a severe metabolic acidosis. Among the few reports of severe starvation ketoacidosis, our case is unique because the patient was monitored closely in an intensive care unit, allowing us to describe the time course of the acidosis in detail. Continue reading >>

Share on facebook

Popular Questions

  1. Cravell

    I found a website or maybe it was a magazine article that described that on a Low-carb/High-protein diet the body will start to convert protein to glucose.

    This process burns additional calories and raises your metabolism. Does anyone know anything about this? I can't find the information anywhere. I think it was called protein glycogenisis.

  2. system

    It's called gluconeogenesis (the creation of new glucose). The nitrogen containing portion of protein is removed in a process called deamination (amino removal) so the body can use then use what is left over as energy. This occurs when muscle protein is used for energy purposes and is generally thought of (by bodybuilders) as a bad thing.

  3. Cravell

    Thanks Joel,

    Yet this site claimed that the body can convert protein from diet in the same way. Is this hogwash?

  4. -> Continue reading
read more close

Related Articles

  • Can Starvation Cause Metabolic Acidosis?

    Abstract Pregnancy is a diabetogenic state characterized by relative insulin resistance, enhanced lipolysis, elevated free fatty acids and increased ketogenesis. In this setting, short period of starvation can precipitate ketoacidosis. This sequence of events is recognized as "accelerated starvation." Metabolic acidosis during pregnancy may have adverse impact on fetal neural development including impaired intelligence and fetal demise. Short per ...

    ketosis Mar 29, 2018
  • Which Metabolic Rate Resulted In Metabolic Acidosis?

    Bicarbonate is the major extracellular buffer in the body. It is present in all body fluids and can be generated from CO2 and H2O in the presence of carbonic anhydrase. Bicarbonate on the chemistry panel gives an indication of acid-base status, but does not replace blood gas measurement as it does not supply information about the respiratory component of acid-base status or the pH of the animal. Bicarbonate values on a chemistry panel should alwa ...

    ketosis Jan 11, 2018
  • What Medications Can Cause Metabolic Acidosis?

    Abstract Metabolic acidosis produced by drugs and/or chemicals can be conveniently divided into those with an increase in the anion gap (anion gap = Na- (Cl + HCO3)) and those with a normal anion gap. The increase in the anion gap is due to the accumulation of unmeasured organic anions, such as lactate or acetoacetate and beta-hydroxybutyrate, as occurs in ketoacidosis and lactic acidosis, or the accumulation of toxic anions such as formate or gl ...

    ketosis Jan 24, 2018
  • How Does Ketoacidosis Cause Metabolic Acidosis

    Metabolic Acids covers all the acids the body produces which are non-volatile. Because they are not excreted by the lungs, they are said to be ‘fixed’ in the body and hence the alternative term fixed acids. All acids other then H2CO3 are fixed acids. Net production of fixed acids is about 1 to 1.5 mmoles of H+ per kilogram per day: about 70 to 100 mmoles of H+ per day in an adult. This non-volatile acid load is excreted by the kidney. Fixed a ...

    ketosis Jan 3, 2018
  • What Is The Cause Of Metabolic Acidosis?

    In the presence of severe, sustained hypocapnia produced in dogs by mechanical hyperventilation, a bicarbonate deficit has been observed. The development of this deficit was progressive and did not terminate at pH compensation. The consequence of this progressive deficit was metabolic acidosis. Simultaneous with the increasing bicarbonate deficit, a rise in lactic and pyruvic acids was observed. Most of the bicarbonate deficit could be accounted ...

    ketosis Mar 29, 2018
  • Why Does Metabolic Acidosis Cause Abdominal Pain

    Patient professional reference Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use. You may find one of our health articles more useful. See also separate Lactic Acidosis and Arterial Blood Gases - Indications and Interpretations articles. Description Metabolic acidosis is defined as an arterial blood pH <7.35 with plasma bicarb ...

    ketosis Dec 26, 2017

Popular Articles

More in ketosis