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Can Starvation Cause Metabolic Acidosis?

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Severe Acidosis Caused By Starvation And Stress.

Severe acidosis caused by starvation and stress. Department of Pediatrics, Children's Hospital of Wisconsin, Milwauke, WI, USA. A 1-year-old boy had severe anoxic brain injury owing to a cardiorespiratory arrest. He had an initial metabolic acidosis, but this largely resolved by hospital day 2. He then had a persistent, profound metabolic acidosis. Evaluation on hospital day 6 found that the patient had ketonemia, ketonuria, and a normal serum glucose level; he had received no intravenous dextrose during his hospitalization. The dextrose-free fluids were given initially to protect his brain from the deleterious effects of hyperglycemia after brain injury. Continuation beyond 24 hours was inadvertent. The initiation of dextrose-containing intravenous fluids produced a rapid resolution of his metabolic acidosis. Starvation usually produces a mild metabolic acidosis, but when combined with physiologic stress, starvation may cause a severe metabolic acidosis. Among the few reports of severe starvation ketoacidosis, our case is unique because the patient was monitored closely in an intensive care unit, allowing us to describe the time course of the acidosis in detail. Continue reading >>

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Popular Questions

  1. Cravell

    I found a website or maybe it was a magazine article that described that on a Low-carb/High-protein diet the body will start to convert protein to glucose.

    This process burns additional calories and raises your metabolism. Does anyone know anything about this? I can't find the information anywhere. I think it was called protein glycogenisis.

  2. system

    It's called gluconeogenesis (the creation of new glucose). The nitrogen containing portion of protein is removed in a process called deamination (amino removal) so the body can use then use what is left over as energy. This occurs when muscle protein is used for energy purposes and is generally thought of (by bodybuilders) as a bad thing.

  3. Cravell

    Thanks Joel,

    Yet this site claimed that the body can convert protein from diet in the same way. Is this hogwash?

  4. -> Continue reading
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