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Can Ketoacidosis Cause Brain Damage

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Diabetic Ketoacidosis Causes, Symptoms, Treatment, And Complications

Diabetic ketoacidosis definition and facts Diabetic ketoacidosis is a life-threatening complication of type 1 diabetes (though rare, it can occur in people with type 2 diabetes) that occurs when the body produces high levels of ketones due to lack of insulin. Diabetic ketoacidosis occurs when the body cannot produce enough insulin. The signs and symptoms of diabetic ketoacidosis include Risk factors for diabetic ketoacidosis are type 1 diabetes, and missing insulin doses frequently, or being exposed to a stressor requiring higher insulin doses (infection, etc). Diabetic ketoacidosis is diagnosed by an elevated blood sugar (glucose) level, elevated blood ketones and acidity of the blood (acidosis). The treatment for diabetic ketoacidosis is insulin, fluids and electrolyte therapy. Diabetic ketoacidosis can be prevented by taking insulin as prescribed and monitoring glucose and ketone levels. The prognosis for a person with diabetic ketoacidosis depends on the severity of the disease and the other underlying medical conditions. Diabetic ketoacidosis (DKA) is a severe and life-threatening complication of diabetes. Diabetic ketoacidosis occurs when the cells in our body do not receive Continue reading >>

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  1. Justin Mulesa

    Depends on your definition of Damage to the brain. It does, by definition, alter the brain chemistry, whether this alteration is beneficial or harmful depends on the baseline state, and effect of the medication. If all brain chemistry alteration was considered damaging, then all psych meds could be considered to cause brain damage (an interesting consideration). However, if the baseline state is itself abnormal, for example in schizophrenia, then dopamine antagonists, such as anti-psychotics, could be and are considered therapeutic. However, with these, and any drugs that alter brain chemistry (and indeed any drug at all) have undesired effects, known as side effects, due to the crudeness and non-specificity medications have. In the brain, even minor fluctuations can have massive consequences. A consequence of dopamine antagonism, at least for the older, less specific, 1st generation anti-psychotics, such as haloperidol, had a cumulative dose side effect which was like Parkinson's disease, known as tardive dyskinesia. Parkinson’s, and a great deal of all motor skills, are very closely linked to dopamine and their receptors, and too much or too little can lead to a decline in motor function. As a dopamine agnoist, as due to the widespread almost ubiquitous negative feedback loop found in physiology, one could conjecture that long term over stimulation of the dopamine tracts could result in a Parkinson’s like disease or other forms of dementia later on down the road, although long term and geriatric studies on adhd medications can be somewhat difficult to come across, here is a link to a simple google search:

  2. Mike Repik

    However that doesn't mean it will. There are a lot of factors. But the big question is, can you solve the problem by any other means than taking a pill which can possibly cause damage?

  3. Brendan Hardy

    There is some evidence to suggest that releasers like Adderall (a proprietary formulation of amphetamine salts) can cause damage to dopamine receptors over long term high dosage use. It appears that Dopamine reuptake inhibitors like Ritalin or Concerta (methylphenidate) have much less risk of brain damage. Now when I say brain damage, I don't mean it'll put you in a coma. It's more likely to kill off some dopamine receptors via overstimulation. As far as I know, the brain is very plasticine and can heal much of the damage over time.

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