Can Alcohol Cause Metabolic Acidosis?

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Alcoholic Ketoacidosis

Background In 1940, Dillon and colleagues first described alcoholic ketoacidosis (AKA) as a distinct syndrome. AKA is characterized by metabolic acidosis with an elevated anion gap, elevated serum ketone levels, and a normal or low glucose concentration. [1, 2] Although AKA most commonly occurs in adults with alcoholism, it has been reported in less-experienced drinkers of all ages. Patients typically have a recent history of binge drinking, little or no food intake, and persistent vomiting. [3, 4, 5] A concomitant metabolic alkalosis is common, secondary to vomiting and volume depletion (see Workup). [6] Treatment of AKA is directed toward reversing the 3 major pathophysiologic causes of the syndrome, which are: This goal can usually be achieved through the administration of dextrose and saline solutions (see Treatment). Continue reading >>

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Popular Questions

  1. Old Forum Import

    What would cause my breath to smell like I've been drinking sometimes and I have not? Nor did I have anything to drink the night before? I've gotten in trouble at work because I suffer from occasional vascular migraines and I look like I'm drinking and now my supervisor says I smelled like I was drinking. I think she's lying -- but could there be a cause? I don't drink because I'm really a chronic dieter and don't want the empty calories.

  2. Doc Kelley

    There are some people that produce alcohol in their intestinal tract from undigested food in excess of normal amounts. This has resulted in incorrect accusations, arrests, and even, in some cases, intoxication without actually drinking alcoholic beverages.

  3. Old Forum Import

    Do you know if any vitamins or minerals taken as
    a daily supplement cause the same smell ??
    Also, do you know if Diflucan taken daily can cause
    a similar smell or interact with other drugs to cause
    an alcohol aroma ??

    kstew likes this.

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