Alcoholic Lactic Acidosis Treatment

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Hemodynamic Consequences Of Severe Lactic Acidosis In Shock States: From Bench To Bedside

Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside Kimmoun et al.; licensee BioMed Central.2015 The Erratum to this article has been published in Critical Care 2017 21:40 Lactic acidosis is a very common biological issue for shock patients. Experimental data clearly demonstrate that metabolic acidosis, including lactic acidosis, participates in the reduction of cardiac contractility and in the vascular hyporesponsiveness to vasopressors through various mechanisms. However, the contributions of each mechanism responsible for these deleterious effects have not been fully determined and their respective consequences on organ failure are still poorly defined, particularly in humans. Despite some convincing experimental data, no clinical trial has established the level at which pH becomes deleterious for hemodynamics. Consequently, the essential treatment for lactic acidosis in shock patients is to correct the cause. It is unknown, however, whether symptomatic pH correction is beneficial in shock patients. The latest Surviving Sepsis Campaign guidelines recommend against the use of buffer therapy with pH 7.15 and issue no recommendation for pH lev Continue reading >>

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Popular Questions

  1. Harken

    Hi guys,
    Since starting my low carb paleo diet its become more healthy oil based ie paleo keto...i feel great.
    However ive lost 18 Lbs (8.2kg) in a month ...i was 19 stone 10, 125.4 kg, 276 Lbs. And havent been hungry as i eat 1kg, 2.2 Lbs of vegetables a day and enough oil through nuts and a tablespoon of coconut oil that im rarely hungry.
    What are the problems with loosing weight too fast? How much weight can i healthily loose being such a chunky bunny? Peace lol

  2. TurtIe

    As long as you're eating a nutrient rich diet and getting the appropriate macros you should be perfectly fine. You have a lot of unnecessary weight at the moment, the rate of loss will slow as your weight drops to value more suited to your height and body composition.

  3. DerekP

    That's awesome. Great job getting started! The fact that you're not getting hungry is a really good sign that your body is taking to keto well.
    You can expect to lose 1 to 3 pounds a week till you get within 15 to 40 lbs of your goal weight. It'll probably slow some at that point. This is going to vary from person to person. You may hit a plateau or 3 in the process. When you do, popping out of keto for a day or two and indulging in some carbs can be effective. When you get closer to your goal weight, switching to some sort of cyclic low-carb protocol may be the next step.
    You're unlikely to see the same rate of fat loss as in the first month because a lot of the weight lost when you started was from your muscles losing water. Like 5 to ten pounds of water leave when your muscles empty of glycogen. This is normal and not unhealthy.
    Losing weight too fast is mostly only unhealthy if you're starving or losing muscle. Keto diets defend muscle pretty well. Doing some resistance training helps as well. You can lose weight too fast, but if you're feeling healthy, sleep well, and not seeing a drop in performance at the gym, then you're probably doing great.
    How much weight can you lose? That's not really for anyone else to say. Now that you've made a decision to be healthier, the sky is really the limit. You can get as fit as you want to be, as strong as you want to be. It's just a matter of time and priorities.

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