Alcohol Lactic Acidosis Mechanism

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Metabolic Abnormalities In Alcoholic Patients: Focus On Acid Base Andelectrolyte Disorders

E-mail: [emailprotected] , [emailprotected] Received Date: December 20, 2014; Accepted Date: January 24, 2015; Published Date: January 27, 2015 Citation: Moses Elisaf MD, Rigas Kalaitzidis MD (2015) Metabolic Abnormalities in Alcoholic Patients: Focus on Acid Base and Electrolyte Disorders. J Alcohol Drug Depend 3:185. doi:10.4172/2329-6488.1000185 Copyright: 2015 Moses Elisaf MD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Alcoholic patients commonly develop a variety of acid-base and electrolyte disturbances. The aim of this review is to describe the most commonly encountered abnormalities and their significant role in the patients morbidity and mortality. Physicians should be aware of these clinically important disturbances caused by alcohol abuse and their underlying pathophysiological mechanisms involved for their appropriate management. Alcoholic Keto Acidosis (AKA) is a medical emergency is more common than previously thought and is characterized by an increased anion gap metabo Continue reading >>

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  1. sharidoto


  2. ljessica0501

    It varies for everyone. For me personally...it took 4 days to register anything and almost 2 weeks to get purple...I have never seen the darkest purple shade. Some people will tell you not to use the sticks, but I like them. My doctor told me to use them 3 times a day for a week to see when my body is the highest. Again...everyone is different. I am highest in the morning, but I hear some people are highest at night.
    Your goals, minus your doubts, equal your reality. - Ralph Marston

  3. PeeFat

    Your body has to burn off all the stored sugar before it goes into ketosis. The shade on the stick should read ' moderate. ' Any higher means you aren't drinking enough water to flush out excess ketones. Too many ketones in your body is unhealthy. So don't think you have to be in the darkest purple range to be eating properly. Also the best time to test is first thing in the morning. Only diabetics need check more than once a day. On atkins we don't even need to use keto sticks. If you follow the rules you will be in ketosis.

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Alcoholism is disease, heres some resources to help you fight back: Responsible Drinking: A Moderation Management Approach http://amzn.to/1ZdgP9f I Need to Stop Drinking!: How to get back your self-respect. http://amzn.to/1VEqbeU Why You Drink and How to Stop: A Journey to Freedom: http://amzn.to/1Q8pAv2 Alcoholics Anonymous: The Big Book: http://amzn.to/1N0rttl Alcoholics: Dealing With an Alcoholic Family Member, Friend or Someone You Love: http://amzn.to/1j9cvH4 Watch more How to Understand Alcoholism videos: http://www.howcast.com/videos/517398-... The question that has been asked of me is if alcoholism can lead to diabetes. And if so, how? The answer is chronic alcohol use can lead to diabetes. The way it leads to diabetes is that chronic alcohol use can cause inflammation of the pancreas, and chronic inflammation of the pancreas can affect the production of insulin in the body. And that's what causes diabetes. So that is why alcohol can be an actual primary determinate of diabetes. The other way that heavy alcohol use can lead to diabetes or exacerbate diabetes is that alcohol has a high content of sugar. So if one is already diabetic, alcohol is really not indicated because of its sugar content. So, again, alcohol can actually be a primary cause of diabetes by chronically inflaming the pancreas, or it can actually make diabetes worse and interfere with the diabetes treatment because of the high sugar content in alcohol.

Alcoholism And Lactic Acidosis

Learn more about the SDN Exhibition Forums for exclusive discounts and contests. So the way I understood this is that both alcohol metabolism and latcate to pyrvuate conversion require NAD, and with too much alcohol consumption the body uses up all the NAD for alcohol metabolism right? The part that I'm a bit troubled with this mechanism is that unless we are doing extreme exercise, we don't really generate lactic acid. In most cases, the body uses oxidative phosphorylation, right? So lactic acidosis will most likely occur when you drink alcohol and then do extreme exercise, correct? SDN Members don't see this ad. About the ads. My understanding is that high NADH levels from EtOH metab drives the pyruvate -> lactate conversion. So you don't need to be exercising +drinking, either will do it on their own. I actually enjoy your questions, though some things are really easily looked up. The several different causes of lactic acidosis: I actually enjoy your questions, though some things are really easily looked up. The several different causes of lactic acidosis: But the reasons behind why lactic acidosis occurs for these is significantly different.... For example, in exercise- lactic Continue reading >>

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  1. Swarley515

    Having trouble bumping from "moderate" ketosis to something stronger. These are my averages (over the last 10 days). For the record, female, 5"5', about 132 now, looking to get to 120. Any ideas on how to move past moderate? and why I have such low ketones in the morning?
    Fat 105g
    Fat % of day 64.5%
    Saturated Fat 42.9g
    Cholesterol 258mg
    Sodium 2188
    Carbs 40.58
    Carbs % of day 11.36%
    Fiber 15.85
    Net Carbs 24.63
    Sugars 11.85
    Protein 89.45
    Protein % of day 24.18%

  2. cruisecontrolx

    There is no "level" of ketosis. Throw the sticks away, they'll just cause you frustration. You're either in ketosis or you aren't.
    If they're showing color, you have gone into ketosis.

  3. Vhyrrimyr

    Being in ketosis is like being pregnant, you either are or you aren't, there's no such thing as "moderate" ketosis.
    Ketostix only measure excess ketones in urine. For someone in nutritional ketosis, a darker color is usually a sign of dehydration. After you've been consistently in ketosis for a longer period of time, the color will be even fainter or negative as your body adapts to using ketones as a primary source of fuel.
    Those sticks are marketed toward type-1 diabetics testing for ketoacidosis and are useless for anyone trying maintain long-term nutritional ketosis.

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this will be a series of lectures to illustrate in simple and precise way how you can manage acid-base imbalance in practical step by step approach.

Metabolic Acidosis In The Alcoholic: A Pathophysiologic Approach.

Metabolic acidosis in the alcoholic: a pathophysiologic approach. Halperin ML , Hammeke M , Josse RG , Jungas RL . The purpose of this paper is to review the acid-base abnormalities in patients presenting with metabolic acidosis due to acute ethanol ingestion and to review the theoretical constraints on ethanol metabolism in the liver. Alcohol-induced acidosis is a mixed acid-base disturbance. Metabolic acidosis is due to lactic acidosis, ketoacidosis and acetic acidosis but the degree of each varies from patient to patient. Metabolic alkalosis is frequently present due to ethanol-induced vomiting. However, it could be overlooked because of an indirect loss of sodium bicarbonate (as sodium B-hydroxybutyrate in the urine). Nevertheless, the accompanying reduction in ECF volume may play an important role in the pathogenesis of alcoholic acidosis because it could lead to a relative insulin deficiency. Treatment of alcohol acidosis should include sodium, chloride, potassium, phosphorus, magnesium and thiamine replacements along with attention to concomitant clinical problems. Unless hypoglycemia is present, glucose need not be given immediately. We feel that insulin should be withheld Continue reading >>

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  1. FitnessJunkie

    Does caffeine negatively affect the Keto Diet?

    I heard someone say the other day that caffeine throws a wrench in the Keto diet. I hope not as I'd like to continue drinking Green Tea and such. Can anyone fill me in?

  2. Negatron617

    most people here would say not and would admit to drinking a couple cups of coffee per day....just watch what you put in the coffee as in how much carbs you put in

  3. fleshmachine

    I drink black coffee before a workout to get me goin', I haven't had any probs with staying/going in ketosis.

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