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Alcohol Associated Lactic Acidosis

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Hemodynamic Consequences Of Severe Lactic Acidosis In Shock States: From Bench To Bedside

Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside Kimmoun et al.; licensee BioMed Central.2015 The Erratum to this article has been published in Critical Care 2017 21:40 Lactic acidosis is a very common biological issue for shock patients. Experimental data clearly demonstrate that metabolic acidosis, including lactic acidosis, participates in the reduction of cardiac contractility and in the vascular hyporesponsiveness to vasopressors through various mechanisms. However, the contributions of each mechanism responsible for these deleterious effects have not been fully determined and their respective consequences on organ failure are still poorly defined, particularly in humans. Despite some convincing experimental data, no clinical trial has established the level at which pH becomes deleterious for hemodynamics. Consequently, the essential treatment for lactic acidosis in shock patients is to correct the cause. It is unknown, however, whether symptomatic pH correction is beneficial in shock patients. The latest Surviving Sepsis Campaign guidelines recommend against the use of buffer therapy with pH 7.15 and issue no recommendation for pH lev Continue reading >>

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Popular Questions

  1. Viking Warrior

    I´m really focusing all my cravings I have on 1 day the next month. I do not have as terrible cravings as on a high carb diet but I still would like to gorge myself once in a while and eat what ever I like too. The food I choose when I have my cheat meals are about 70% carbs and most of it sugar. I really need these meals to stop all the thoughts I have on eating other things than what I´m supposed to between my cheat meals. Tomorrow I start my third week with my low carb diet and on the day I plan to have my cheat meal I have been on my low carb diet almost 5 weeks.
    My question is:
    What will happen to my keto adaption if I after 5 weeks of strict low carb eating (less then 100g per day without cheat meals) have a HUGE carbmeal with about 5000-10000kcal where 70% is carbs. I will not eat this in 1 hour but maybe in one evening in front of a couple of movies. I´m not joking, I usually eat huge cheat meals with alot of calories but this day is a special event for me and that´s why it may be a little bigger than a usual cheat meal.
    What will happen with my keto adaption with 1 HUGE cheat meal or cheat evening? I will go back to low carb again the first thing next morning. Will I have start the whole keto adaption over from day one with low energy a few weeks again?

  2. ogella

    For me, it takes about 2 to 3 days after a huge carb meal to return to ketosis. And it takes about 4 to 5 days for me to start losing again.

  3. glorth2

    5k-10k? What are you eating?

  4. -> Continue reading
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