What Is The Duration Of Regular Insulin?

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Insulin (medication)

"Insulin therapy" redirects here. For the psychiatric treatment, see Insulin shock therapy. Insulin is used as a medication to treat high blood sugar.[3] This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It is also used along with glucose to treat high blood potassium levels.[4] Typically it is given by injection under the skin, but some forms may also be used by injection into a vein or muscle.[3] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] Insulin can be made from the pancreas of pigs or cows.[5] Human versions can be made either by modifying pig versions or recombinant technology.[5] It comes in three main types short–acting (such as regular insulin), intermediate–acting (such as NPH insulin), and longer-acting (such as insulin glargine).[5] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.[6] It is on the Continue reading >>

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  1. Lloyd

    Types of Insulin

    Insulin is divided into types, based on how long it is active in your body. This helps match insulin with a specific need.
    Rapid Acting
    Intended to be taken at the same time as meals
    Humalog or lispro
    Onset: 15-30 minutes
    Peak 30-90 minutes
    Duration 3-5 hrs
    Should be taken 15 minutes before or immediately after a meal

    Humalog Prescribing Info
    Novalog, AKA Novorapid, aspart
    Onset: 5-10 minutes
    Peak: 40-50 minutes
    Duration: 3-5 hrs
    Should be given 5-10 minutes before the start of a meal

    Novolog Prescribing Info
    Apidra or glulisine

    Onset: 20-30 minutes
    Peak: 60-90 minutes
    Duration: 1-2.5 hrs
    Take 15 minutes before to 20 minutes after starting a meal

    Apidra Prescribing Info
    Intended for meals eaten within 30 - 60 minutes
    Onset: 30-60 minutes
    Peak 2-5 hrs

    Duration: 5-8 hrs

    Onset: 30-60 minutes
    Peak: 2-5 hrs

    Duration 5-8 hrs
    Covers your needs for half a day, or overnight
    Onset: 2-4 hours
    Peak: 4-12 hours

    Duration: 12-18 hours

    U-500 insulin is regular insulin in 500 units/mL concentration (as opposed to the standard 100 units/mL). Useful for extreme insulin resistance (with typical daily requirements over 200 units/day).

    Onset: 1.5 hrs
    Peak: 4-8 hrs

    Duration: 24 hours
    Intended to last a day
    Ultralente (no longer manufactured)
    starts working in 4-6 hours

    active well beyond 32 hours.
    Onset 3-4 hours
    Peak 6-8 hours
    Duration 18-24 hrs

    information for Lantus®.
    Levemir or Detemir

    Used once or twice a day

    Levemir® Prescribing Information
    Insulin Mixtures
    Starts working in 30 minutes and is active 16 to 24 hours.
    Usually taken twice a day at mealtimes

    There are several variations with different proportions of the mixed insulins.

    Humulin 70/30
    Novolin 70/30
    Novolog 70/30
    Humulin 50/50

    Humalog mix 75/25
    This is a work in progress. Contributions welcomed, please send me a PM
    Thanks to saraknic for the cool formatting!
    Thanks to skessdtrek for the U-500 info.

  2. drewgolden

    Another very nice contribution from Lloyd!

  3. RainLover

    Would you kindly advise from where did you obtained the information that the duration time for Apidra is 1 to 2.5 hours.

  4. -> Continue reading
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