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What Is The Duration Of Regular Insulin?

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Insulin (medication)

"Insulin therapy" redirects here. For the psychiatric treatment, see Insulin shock therapy. Insulin is used as a medication to treat high blood sugar.[3] This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It is also used along with glucose to treat high blood potassium levels.[4] Typically it is given by injection under the skin, but some forms may also be used by injection into a vein or muscle.[3] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] Insulin can be made from the pancreas of pigs or cows.[5] Human versions can be made either by modifying pig versions or recombinant technology.[5] It comes in three main types short–acting (such as regular insulin), intermediate–acting (such as NPH insulin), and longer-acting (such as insulin glargine).[5] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.[6] It is on the Continue reading >>

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Popular Questions

  1. Lloyd

    Types of Insulin

    Insulin is divided into types, based on how long it is active in your body. This helps match insulin with a specific need.
    Rapid Acting
    Intended to be taken at the same time as meals
    Humalog or lispro
    Onset: 15-30 minutes
    Peak 30-90 minutes
    Duration 3-5 hrs
    Should be taken 15 minutes before or immediately after a meal

    Humalog Prescribing Info
    Novalog, AKA Novorapid, aspart
    Onset: 5-10 minutes
    Peak: 40-50 minutes
    Duration: 3-5 hrs
    Should be given 5-10 minutes before the start of a meal

    Novolog Prescribing Info
    Apidra or glulisine

    Onset: 20-30 minutes
    Peak: 60-90 minutes
    Duration: 1-2.5 hrs
    Take 15 minutes before to 20 minutes after starting a meal

    Apidra Prescribing Info
    Short-acting
    Intended for meals eaten within 30 - 60 minutes
    Humulin
    Onset: 30-60 minutes
    Peak 2-5 hrs

    Duration: 5-8 hrs
    Novolin

    Onset: 30-60 minutes
    Peak: 2-5 hrs

    Duration 5-8 hrs
    Intermediate-acting
    Covers your needs for half a day, or overnight
    NPH
    Onset: 2-4 hours
    Peak: 4-12 hours

    Duration: 12-18 hours
    U500

    U-500 insulin is regular insulin in 500 units/mL concentration (as opposed to the standard 100 units/mL). Useful for extreme insulin resistance (with typical daily requirements over 200 units/day).
    Lente

    Onset: 1.5 hrs
    Peak: 4-8 hrs

    Duration: 24 hours
    Long-acting
    Intended to last a day
    Ultralente (no longer manufactured)
    starts working in 4-6 hours

    active well beyond 32 hours.
    Lantus
    Onset 3-4 hours
    Peak 6-8 hours
    Duration 18-24 hrs

    information for Lantus®.
    Levemir or Detemir

    Used once or twice a day

    Levemir® Prescribing Information
    Insulin Mixtures
    Starts working in 30 minutes and is active 16 to 24 hours.
    Usually taken twice a day at mealtimes

    There are several variations with different proportions of the mixed insulins.


    Humulin 70/30
    Novolin 70/30
    Novolog 70/30
    Humulin 50/50

    Humalog mix 75/25
    This is a work in progress. Contributions welcomed, please send me a PM
    Thanks to saraknic for the cool formatting!
    Thanks to skessdtrek for the U-500 info.
    -Lloyd

  2. drewgolden

    Another very nice contribution from Lloyd!
    Thanks!
    drew

  3. RainLover

    Would you kindly advise from where did you obtained the information that the duration time for Apidra is 1 to 2.5 hours.
    Thanks

  4. -> Continue reading
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