What Is Insulin Glargine

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What Is The Best Form Of Insulin For Diabetes? Synthetic Or Human Insulin And Why?

We want to mimic the body's own insulin by injecting insulin of different kinds multiple times a day. First we need a super-stable super-long acting insulin which will be continuously effective over 24+ hours, without troughs and peaks, only the newest synthetic analogues do this, the most stable being Novo Nordisk's new Insulin degludec (Tresiba®), before that we had Aventis' quite acceptable Insulin glargine (Lantus®) and NovoNordisk's Insulin detemir (Levemir®). As you can see the glucose needed to be infused to keep the blood glucose level steady over time after Insulin Degludec is stable, but after 8-10 hours rises, peaking at 14-16 hours and going down a lot at 18-20 hours after Insuline Glargine injection: So Insulin Degludec seems more stable than Insulin Glargine. We also want the effect of an insulin to be consistent (the same after each injection on different days): You can see why the old NPH insulin has had its day, peaking at 8 hours and losing potency after 16 hours: If the pancreas is still making enough insulin to regulate the blood sugar after meals, we only need one usually injection of a super long acting insulin analogue before bedtime to keep the blood suga Continue reading >>

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Popular Questions

  1. Lucywestie

    A friend of mines son has Diabetes and as such has to travel with his meds in his carry on. They will be going to Scotland in August and Im wondering what is the best and legitimate way to keep the Insulin cool for the flights.
    I have heard of everything from bags of ice that will melt enroute to the permanent Ice packs. Just wondering what others do that travel regularly with meds that have to be kept cold. Bear in mind that they also have to keep approximately 2 weeks worth cool so that they have enough while on their holiday.

  2. emel49

    Why not ask the FA to keep it in the fridge in the galley?

  3. TravellerPlus

    I work in a hospital. The Pharmacy suppiles our insulins to the medication refrigerator, but the bottles are labelled good for 28 days when stored at room temp; the CPS agrees (even for insulin glargine [Lantus] which we used to keep cool at all times).
    Your friend should double check with her Pharmacist, but I suspect that the insulin should be fine if not kept in a fridge whilst on board the plane.

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    Next tab » This is a summary of the European public assessment report (EPAR) for Lantus. It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Lantus. Name Language First published Last updated Lantus : EPAR - Summary for the public Select a language to view the documentBG = bălgarsk ...

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  • What Is Insulin Glargine Used For

    Indication BASAGLAR is a long-acting insulin used to control high blood sugar in adults and children with type 1 diabetes and adults with type 2 diabetes. Limitation of Use BASAGLAR is not for treating diabetic ketoacidosis. Important Safety Information Do not take BASAGLAR during episodes of low blood sugar or if you are allergic to insulin glargine or any of the ingredients in BASAGLAR. Do NOT reuse needles or share insulin pens, even if the ne ...

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    Insulin glargine, marketed under the names Lantus, among others, is a long-acting basal insulin analogue, given once daily to help control the blood sugar level of those with diabetes. It consists of microcrystals that slowly release insulin, giving a long duration of action of 18 to 26 hours, with a "peakless" profile (according to the insulin glargine package insert). Pharmacokinetically, it resembles basal insulin secretion of non-diabetic pan ...

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  • Who Insulin Glargine

    Dosage Forms & Strengths injectable solution 100 units/mL (Lantus; 10mL vial) 100 units/mL (Lantus SoloSTAR; Basaglar KwikPen; 3 mL disposable prefilled pens) 300 units/mL (Toujeo; 1.5 mL SolosStar disposable prefilled pen) Note: Recent studies have suggested that glargine-300 extends blood glucose control well beyond 24 hr Type 1 or 2 Diabetes Mellitus Lantus and Toujeo are recombinant human insulin analogs indicated to improve glycemic control ...

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  • Why Can't Glargine Insulin Be Mixed

    Draft1 Prescribing Information as of April 20002 LANTUS®3 (insulin glargine [rDNA origin] injection)4 LANTUS® must not be diluted or mixed with any other insulin or solution.5 DESCRIPTION6 LANTUS® (insulin glargine [rDNA origin] injection) is a sterile solution of insulin glargine for use7 as an injection. Insulin glargine is a recombinant human insulin analog that is a long-acting (up to 24-8 hour duration of action), parenteral blood-g ...

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  • Insulin Glargine Dose

    Applies to the following strengths: 100 units/mL; 300 units/mL The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist. Usual Adult Dose for Diabetes Type 1 Dose should be individualized based on clinical response; this basal insulin should be used in regimens with short-acting insulin Initial dose: One-third to one-half the total daily insulin requirement subcutaneously once a day Maintenance ...

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