What Insulin Resistance

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What Is Insulin Resistance?

Insulin is a hormone produced by the pancreas that helps unlock the body's cells so that sugar (glucose) from the food we eat can be used by the cells for energy. In people with type 2 diabetes, a combination of problems occurs, and scientists aren't really sure which is the chicken and which is the egg. The person's body may not be producing enough insulin to meet their needs, so some glucose can't get into the cells. Glucose remains in the bloodstream, causing high blood glucose levels. In many cases, the person may actually be producing more insulin than one might reasonably expect that person to need to convert the amount of food they've eaten at a meal into energy. Their pancreas is actually working overtime to produce more insulin because the body's cells are resistant to the effects of insulin. Basically the cells, despite the presence of insulin in the bloodstream, don't become unlocked and don't let enough of the glucose in the blood into the cells. Scientists don't know exactly what causes this insulin resistance, and many expect that there are several different defects in the process of unlocking cells that cause insulin resistance. Medications for type 2 diabetes focus Continue reading >>

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Popular Questions

  1. Ron Hunter

    A lot of it seems to be fat cells possibly being the start. I’m not certain that the exact mechanisms are known. There are links between fat cells being able to expand (fat wise) but also links between inflammation in fat cells. The main protein that works with insulin in the body, GLUT4, works in fat cells and muscle cells. There are also links between where and what type of fat is in the body and insulin resistance. In addition, fat cells also secrete things like cytokines that may play a role.

  2. Steve Kirsch

    The reason you are insulin resistant because you are drowning your body in blood sugar for most of the day forcing insulin to be pumped out all the time in high doses and sometimes in very large spikes (like for addressing refined carbs).

  3. Patrick Ira DonEgan

    One of the main things not usually discussed is the levels of certain solvents that enter the human body and how they are related to health.

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