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What Causes A Lack Of Insulin?

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The Role Of Insulin In The Body

Tweet Insulin is a hormone which plays a key role in the regulation of blood glucose levels. A lack of insulin, or an inability to adequately respond to insulin, can each lead to the development of the symptoms of diabetes. In addition to its role in controlling blood sugar levels, insulin is also involved in the storage of fat. Insulin is a hormone which plays a number of roles in the body’s metabolism. Insulin regulates how the body uses and stores glucose and fat. Many of the body’s cells rely on insulin to take glucose from the blood for energy. Insulin and blood glucose levels Insulin helps control blood glucose levels by signaling the liver and muscle and fat cells to take in glucose from the blood. Insulin therefore helps cells to take in glucose to be used for energy. If the body has sufficient energy, insulin signals the liver to take up glucose and store it as glycogen. The liver can store up to around 5% of its mass as glycogen. Some cells in the body can take glucose from the blood without insulin, but most cells do require insulin to be present. Insulin and type 1 diabetes In type 1 diabetes, the body produces insufficient insulin to regulate blood glucose levels. Continue reading >>

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Popular Questions

  1. molson1959

    lack of insulin or insulin resistance

    Greetings members,
    As a newbie T2, i have lots of questions as i am sure a lot of you had.
    Can someone tell me in general terms how treatment differs with the two distinct diabetes problems mentioned above.
    I have looked through the forums but did not find what i was looking for, if this has been covered previously, accept my opologizes and perhaps direct me to the correct thread
    Thanks in advance
    mike

  2. jwags

    Welcome Mike to DD. Lack of insulin or insulin insufficiency can be tested by a C Peptide test. Insulin resistance can also be tested with a C Peptide. If you have a high level of insulin and high fasting numbers you probably are insulin resistant. A very low number may indicate lack of insulin. Once your beta cells are damaged they usually don't regenerate and you will probably need injected insulin.

  3. Lynnw

    From what I've read, a lot of doctors don't make the distinction between IR and insulin insufficiency. To my doctor, high blood sugar is the issue...WHY it's high is irrelevant. He started going down his list of medications, starting with Metformin. If it didn't work, he'd shrug and try the next drug on the list. I had to beg him to do tests (except lipids...he was crazy for lipid tests, even though mine were good every time). I want answers, so I wasn't happy with that. Seems to me you'd want to know WHY it's high to determine the best treatment.

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