Must Insulin Be Stored In The Refrigerator?
I have a newly diagnosed diabetic dog on NPH insulin, whose owner has not been refrigerating the insulin (Novolin N). I instructed him to store the open insulin vial in the refrigerator. However, the pharmacy where he purchased the insulin put a sticker on the vial that says it can be left at room temperature. The owner also claims he looked it up online and says it doesn't have to be refrigerated. I have always been taught that insulin must remain in the refrigerator or it loses it's "potency." I did look up the FDA Patient Package Insert online, which says the following: All Unopened Novolin N: Keep all unopened Novolin N in the refrigerator between 36° to 46°F (2° to 8°C). Do not freeze. Do not use Novolin N if it has been frozen. If refrigeration is not possible, the unopened vial may be kept at room temperature for up to 6 weeks (42 days), as long as it is kept at or below 77°F (25°C). Keep unopened Novolin N in the carton to protect from light. Opened Novolin N Vials: Keep at room temperature below 77°F (25°C) for up to 6 weeks (42 days). Keep vials away from direct heat or light. Throw away an opened vial after 6 weeks (42 days) of use, even if there is insulin left Continue reading >>