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Short Acting Insulin

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Novo Nordisk Receives Fda Approval For Fiasp®, A New Fast-acting Mealtime Insulin

® (insulin aspart injection) 100 Units/mL, a fast-acting mealtime insulin indicated to improve glycemic control in adults with type 1 and type 2 diabetes.1 Fiasp® can be dosed at the beginning of a meal or within 20 minutes after starting a meal. Fiasp® is a new formulation of NovoLog®, in which the addition of niacinamide (vitamin B3) helps to increase the speed of the initial insulin absorption, resulting in an onset of appearance in the blood in approximately 2.5 minutes.2 Fiasp® will be available in a pre-filled delivery device FlexTouch® pen and a 10 mL vial.1 Many adults with type 1 and type 2 diabetes struggle with blood sugar control after meals. The result of this has led to many people with diabetes not achieving their target A1C. "With Fiasp®, we've built on the insulin aspart molecule to create a new treatment option to help patients meet their post-meal blood sugar target," said Bruce Bode, MD FACE, President of Atlanta Diabetes Associates and Associate Professor at Emory University School of Medicine. "The intention of rapid acting insulin therapy is to mimic, as much as possible, the natural physiological insulin response that occurs after meals, a process tha Continue reading >>

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Popular Questions

  1. Dr. Dave

    Dr. Dave :
    Hello, and thanks for writing in. How much chocolate did she eat, and what kind of chocolate was it (i.e. milk chocolate, dark chocolate, etc.)?
    Customer:
    We think it was a small bar of milk chocolate and I gave her 2 extra units of insulin when we realised as just before she had eaten some more meat at dinner time and that was before we noticed the chocolate. She was looking rather unwell before looking as if she may be sick but wasn't and is now lying down having a sleep.
    Dr. Dave :
    Thanks for your reply. How large was the small bar of milk chocolate (i.e. how many ounces or grams)?
    Customer:
    Afraid I can't say exactly - maybe about 10 - 20 grams - no bigger than a mini sized choc. bar that you get in a multi-pack
    Dr. Dave :
    Thank you. That amount in a Pomeranian might cause vomiting and/or diarrhea, but is not a toxic amount (i.e. you won't likely see further symptoms such as abnormal heart rate or neurologic symptoms). Giving the extra insulin is fine, just make sure that Candy eats throughout the day to make sure her blood glucose stays high enough. If you happen to see any symptoms that don't resolve on their own through the day, then it would be best to get her into a veterinarian for more specific treatment, but I would say that overall she should be fine.
    Customer:
    Thanks for your advice. When I said she looked rather unwell before she was presenting with rapid, shallow breathing and a fast heartbeat and was whimpering a bit which was when I thought she may be going to vomit. She did not vomit and as I said before she is now lying down, sleeping. Her heartbeat and breathing appear normal again and she seems a lot happier than she was. Should I give her the other 2.5 units of insulin if she eats later on and if she refuses food should i refrain from the other units of insulin for today? Should I worry if she has diarrhea or vomits?
    Dr. Dave :
    Yes - I would give another 2.5 units if she eats later on, but I would not give the insulin if she doesn't eat. I would not worry if she has a small amount (or a couple episodes) of vomiting or diarrhea. But, if the symptoms persist, or if she's lethargic, then I would get her into a veterinary clinic for an exam and treatment, especially since she has diabetes - I just wouldn't take any chances.
    Customer:
    Ok. Thank you so much your advice has been very re-assuring and clear.
    Dr. Dave :
    Thank you - I appreciate your kind words! Glad to be here to help out. I hope you and Candy have a good rest of the day.

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