Prednisone And Insulin

Share on facebook

Prednisone And Diabetes: What Is The Connection?

Prednisone is a steroid that works in a similar way to cortisol, which is the hormone normally made by the body's adrenal glands. Steroids are used to treat a wide range of conditions from autoimmune disorders to problems related to inflammation, such as arthritis. They work by reducing the activity of the body's immune system and reducing inflammation and so are useful in preventing tissue damage. However, steroids may also affect how the body reacts to insulin, a hormone that controls the level of sugar in the blood. Contents of this article: How do steroids affect blood sugar levels? Steroids can cause blood sugar levels to rise by making the liver resistant to the insulin produced by the pancreas. When blood sugar levels are high, insulin is secreted from the pancreas and delivered to the liver. When insulin is delivered to the liver, it signals it to reduce the amount of sugar it normally releases to fuel cells. Instead, sugar is transported straight from the bloodstream to the cells. This process reduces the overall blood sugar concentration. Steroids can make the liver less sensitive to insulin. They can make the liver carry on releasing sugar even if the pancreas is releasi Continue reading >>

Share on facebook

Popular Questions

  1. NoNora

    I've read a good deal about the high BG experiences of diabetics and several forum members mentioned changing their basal and/or bolus. Could someone be more specific and tell me what they did with their dosages that helped?
    I'm on a 2 week course of this drug and spent my first day largely between 275 and 420 - it took what I consider MASSIVE amounts of insulin to bring it down at all.
    Sadly, I'm in the painful position of the doctors having tried everything else, and this prednisone course is an absolute must -I really can't choose not to take it and would really appreciate any specific advice anyone can offer.
    Also several people mentioned the BG effects lasting AFTER they stopped taking the prednisone. For those of you who have experienced this, how long after.
    Thanks so much.

  2. GrammaBear

    I did not take prednisone, but another steroid in the form of a topical ear drop (which wasn't supposed to elevate my bg, but it did!). I can tell you that my bg was also high like yours and it took massive doses of insulin above what I normally use to bring it anywhere near my target range.
    Please talk with your doctor or at least his nurse or someone who can give you professional advice. I am on a pump and did a increase of 50% temp basal up to an increase of 80% temp basal. In addition to that I changed my insulin to carb ratios in half - meaning if my I:C for a meal was normally 1 unit of insulin for every 10 carbs - I changed it to 1 unit of insulin to every 6 carbs.
    Again you have to "play" with the I:C ratio until you find what works for you. Be cautious when changing your rates especially if this is your first time with prednisone. Oh......and don't forget to check with your doctor.

  3. SueM

    the rule of thumb is it takes about 2 units of insulin to 1 mg of pred. (endo told me this)
    Basically though you need as much insulin as you need.
    Hope this helps.

  4. -> Continue reading
read more close

Related Articles

  • Prednisone And Insulin

    Abstract OBJECTIVES: To determine the effect of low (≤7.5 mg/day; LD-PRD group) or medium (>7.5 mg/day; MD-PRD group) doses of prednisone over the past 4 months on insulin levels and insulin resistance (IR) in SLE patients. METHODS: SLE patients were categorised in prednisone non-users (No PRD) (n=41), LD-PRD (n=71) and MD-PRD (n=16) users. We compared insulin levels, presence of increased IR using homeostasis model assessment (HOMA index), met ...

    insulin Jan 12, 2018
  • Prednisone And Type 1 Diabetes

    Autumn is approaching with its beautiful fall foliage, hayrides at the pumpkin patch, and harvest festivals, as well as its sniffles and running noses. Cold and flu season is a drab for everyone, but can be particularly worrisome for people with diabetes. In addition to worrying about how being sick will affect their glucose levels and whether or not cold and flu medications are sugar free, being prescribed corticosteroid (steroids) adds a whole ...

    diabetes Jan 16, 2018
  • Is Prednisone Induced Diabetes Reversible

    Good nutrition is key Betty Overfelt's oncologist back home in Missouri informed her that she had stage IV small-cell lung cancer. His prognosis was grim — "I think I can get you three months if you'll take treatment," he said. Jerry, her husband of 45 years, decided immediately to seek a second opinion, which led them to Cancer Treatment Centers of America© (CTCA). There, Jerry remembered, doctors told Betty that they couldn't promise a cure ...

    diabetes Jan 16, 2018
  • Does Prednisone Raise Blood Sugar

    By the dLife Editors Some medicines that are used for treating other medical conditions can cause elevated blood sugar in people with diabetes. You may need to monitor your blood glucose more closely if you take one of the medicines listed below. It’s important to note that just because a medicine has the possibility of raising blood sugar, it does not mean the medicine is unsafe for a person with diabetes. For instance, many people with type 2 ...

    blood sugar Feb 9, 2018
  • Prednisone Diabetes

    Diabetes is a chronic disease that can affect dogs and cats and other animals (including apes, pigs, and horses) as well as humans. Although diabetes can’t be cured, it can be managed very successfully. Diabetes mellitus, or “sugar diabetes,” is the type of diabetes seen most often in dogs. It is a metabolism disorder. Metabolism refers to how the body converts food to energy. To understand what diabetes is, it helps to understand some of t ...

    diabetes Feb 9, 2018
  • Prednisone Causes Diabetes

    Unfortunately, many people who suffer from Crohn’s disease also have to cope with some form of diabetes. The long-term use of oral corticosteroids, like prednisone, as a treatment for Crohn’s disease has been linked with both steroid-induced and type 2 diabetes. For this reason, among many others, most physicians counsel against the long-term use of steroids for the treatment of Crohn’s. Realistically, however, steroids are often a necessar ...

    diabetes Jan 30, 2018

Popular Articles

More in insulin