Metformin Pros And Cons

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Managing Type 2 Diabetes In Patients Not Controlled On Metformin

The incidence and prevalence of diabetes (and especially type 2 diabetes) are increasing worldwide. The World Health Organization (WHO) estimates that worldwide 171 million people suffered from diabetes in 2000, and predicts that by 2030 their number will increase to more than 300 million.1 Due to the initially often silent course of the disease and thus late diagnosis, and also because of gross undertreatment of hyperglycaemia and additional cardiovascular risk factors, diabetes is a major cause of morbidity and mortality. Microvascular complications – such as retinopathy, neuropathy and nephropathy – and macrovascular disease cause human suffering, but are also a major burden to healthcare resources worldwide. The ultimate goal of diabetes therapy is to prevent micro- and macrovascular disease in order to improve life expectancy and quality of life. The Diabetes Control and Complications Trial (DCCT)2 and UK Prospective Diabetes Study (UKPDS)3 demonstrated that lowering glycaemia, which can be measured as glycated haemoglobin (HbA1c), leads to fewer microvascular complications – mainly retinopathy and nephropathy – in type 1 as well as type 2 diabetes, with the lowest ris Continue reading >>

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Popular Questions

  1. Indiana Bones

    Hi guys
    I was diagnosed with PCOS over a year ago. Since the diagnosis, I have been waiting on the public health system to see a gynaecologist. I really don't know whether I really need to see a gynaecologist now though, because since my PCOS diagnosis I've lost over 8kgs (diet and exercise) and a lot of my symptoms have subsided.
    Now when I received my diagnosis from my GP (based on symptoms of PCOS ovaries, facial hair, obesity, lack of periods, high blood pressure), he mentioned to me that when I see the gynaecologist, she/he will probably want to put me on Metformin. Now from what I've read, Metformin is used to insulin problems, is this right? I'm pretty sure that when I had my glucose testing done, I was deemed not insulin resisitive, so I'm just wondering ...
    Do GPs/Gynaecologists tend to put PCOS sufferers on Metformin? If so, why?
    Is there anyone out there not on Metformin? What are the pros and cons?
    I have googled Metformin, but I'm really not understanding why some women are prescribed it and others are not.

  2. misse10

    metformin helps your body get your insulin to work better. i have taken it for insulin resistant PCOS and it helped me drop a lot of weight when diet/exercise couldn't.
    i also took it when pregnant as it's shown to reduce miscarriage rates (for those with PCOS issues) and then late in pregnancy when I got gestational diabetes. I'll be going back on it once i stop breastfeeding.
    i see an endocrinologist to manage by PCOS and am very pleased i've been on it. The slow release formula is on global shortage at the moment, whcih is less liekly to give you an upset tummy/diahorrea.

  3. Paddlepop

    Your GP can prescribe metformin for you. I've been on it for about 5 years now. I'm not diabetic nor do I have PCOS or TTC.
    I have a chronic illness that means that I get episodes that resemble low blood sugar (my blood sugar is fine) and the metformin has evened these out and lessened them. Plus I have a strong family history of Type 2 diabetes so I'm kind of using it as a preventative.
    Like others have said, metformin helps your body to use your insulin more effectively. If you are taking it and become pregnant, you need to stay on it until the end of the first trimester. It helps to prevent miscarriages in those with PCOS. Going off it doing the first trimester could cause a miscarriage.
    Ask your GP to prescribe it and don't wait until you see the gyno.
    Congrats on the weight loss!

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