Insulin And Glucagon Work Antagonistically To Each Other

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Antagonistic Effects Of Insulin Signaling And Glucagon Signaling On Controlling Hepatic Gluconeogenic Gene Expression

Evan Chang and Ling He* Department of Pediatrics, Division of Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA *Corresponding Author: Ling He Division of Metabolism 600 N. Wolfe St, Baltimore MD 21287, USA Tel: 410-502-5765 Fax: 410-502-5779 E-mail: [email protected] Citation: Chang E, He L (2014) Antagonistic Effects of Insulin Signaling and Glucagon Signaling on Controlling Hepatic Gluconeogenic Gene Expression. Pediat Therapeut 4:200. doi:10.4172/2161-0665.1000200 Copyright: © 2014 Chang E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Visit for more related articles at Pediatrics & Therapeutics Abstract With the worldwide epidemics of obesity and diabetes, there is an urgent need for action at the global and national levels to prevent and to treat these metabolic disorders. Inappropriate hepatic glucose production is the major cause of hyperglycemia in obese and diabetic patients. In this mini-review, we summarize the antagonistic effects of insulin sig Continue reading >>

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Popular Questions

  1. Simran Sharma

    Glucagon and insulin are Antagonistic to each other. Justify the statement.

    Glucagon and insulin are Antagonistic to each other. Justify the statement.

  2. Bhageerathan

    Glucagon and insulin are antogonistic to each other.They both are secreted by pancreas.Glucagon is an enzyme whereas insulin is a harmone which regulates blood sugar levels.

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