Insulin And Glucagon Are Both Hormones That Work Opposite To Each Other

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Glucose Metabolism

Energy is required for the normal functioning of the organs in the body. Many tissues can also use fat or protein as an energy source but others, such as the brain and red blood cells, can only use glucose. Glucose is stored in the body as glycogen. The liver is an important storage site for glycogen. Glycogen is mobilized and converted to glucose by gluconeogenesis when the blood glucose concentration is low. Glucose may also be produced from non-carbohydrate precursors, such as pyruvate, amino acids and glycerol, by gluconeogenesis. It is gluconeogenesis that maintains blood glucose concentrations, for example during starvation and intense exercise. The endocrine pancreas The pancreas has both endocrine and exocrine functions. The endocrine tissue is grouped together in the islets of Langerhans and consists of four different cell types each with its own function. Alpha cells produce glucagon. Beta cells produce proinsulin. Proinsulin is the inactive form of insulin that is converted to insulin in the circulation. Delta cells produce somatostatin. F or PP cells produce pancreatic polypeptide. Regulation of insulin secretion Insulin secretion is increased by elevated blood glucose Continue reading >>

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Popular Questions

  1. Dickerson888

    Flexpens jamming

    I use the Novolog Flex pens and I am having trouble with the plunger getting difficult to push or stopping and jamming completely.
    I have had two stop completely and about half get difficult to push.
    I emailed the company and I got a form letter requesting I take them back to the pharmacy.
    Is anyone else having this issue?

  2. davedsel

    I used Flexpens for Victoza for several months and never had this problem.
    I think taking the pens back to the pharmacy would be your best course of action.

  3. auriga1

    Dickerson, I use two insulins, both the pens. I've not had any problems with them now for the past seven years.
    I would definitely take them back to the pharmacy. I hope you saved the ones that have jammed. Just explain exactly what is going on. You need your insulin at the correct dosage.
    At diagnosis, no one taught me how to use the meter. Upon discharge from the hospital, I went to the pharmacy to pick up my new meter. Not a clue how to use it. Read the instructions, blah, blah, blah. I think I was just overwhelmed that I had to test eight times a day and use two different insulins. Just hit me like a brick wall. No one I knew had diabetes and had to test constantly. I think the pharmacist saw my face before I even asked. He was kind enough to sit with me in the store and explain and do a little show-and-tell. I really don't know how many would do that, but I would think more of them are willing to help no matter what is going on.
    Take the pens in and see if they will help. It never hurts to ask.

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