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How To Increase Insulin Production In Pancreas

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Pancreas And Beta-cell Development: From The Actual To The Possible

The development of insulin-producing pancreatic beta (β)-cells represents the culmination of a complex developmental program. Cells of the posterior foregut assume a pancreatic identity, cells within the expanding pancreatic primordia adopt an endocrine fate, and a subset of these precursors becomes competent to generate β-cells. Postnatally, β-cells are primarily maintained by self-duplication rather than new differentiation. Although major gaps in our knowledge still persist, experiments across several organisms have shed increasing light on the steps of β-cell specification and differentiation. Increasing our understanding of the extrinsic, as well as intrinsic, mechanisms that control these processes should facilitate efforts to regenerate this important cell type in humans. The pancreas serves two major functions: (i) the production of digestive enzymes, which are secreted by exocrine acinar cells and routed to the intestine by a branched ductal network; and (ii) the regulation of blood sugar, which is achieved by endocrine cells of the islets of Langerhans. Type 1 diabetes results from the autoimmune destruction of one islet cell type - the insulin-producing β-cells. Alt Continue reading >>

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Popular Questions

  1. MariaKhristine

    Hi ladies,
    I’ll be getting my first-ever CGM next week, but I’m a little concerned about where to put the sensor. I do not want it to show, so I don’t like the arm. I’ve never given shots in my stomach before, and I’m very uncomfortable with putting it on my stomach. (I don’t have a pump.)
    I’m thinking of either my thigh or butt/hip. My wardrobe is a lot of pencil skirts/dresses, and pants that tend to be tighter around the hip/upper thigh area, though, so I wonder how those locations would impact my clothing. I was thinking of maybe putting some type of a garter over the sensor to try to smooth it out? Most of my research on garters has discussed only pumps, though, and not the CGM sensors, so I’m not sure if there are other products or other things I can do so I can keep wearing the clothes I like wearing, but also not be uncomfortable wearing the sensor.
    Finally, does the sensor impact your sexual activity? That is my one worry about having it on my thigh/butt/hip.

    Thanks so much; I’m hoping I might get a few ideas from some of you.

  2. Jenpsu2

    Hi-
    I don’t have a pump either and was also worried about where to put the Dexcom sensor so that it would not be noticable.
    I either wear it low on my stomach or on my hip towards the back. My hip is my favorite spot and I don’t have a problem with it showing through clothes. My only issue is if it is too close to the waistband of my pants/skirt- sometimes I pull it off by accident.

  3. system

    I wear mine on my butt. There is a noticeable lump there if your pants or skirts are form fitting. No one has ever asked me or comment about it though. The only other place I’ve tried it is my lower back near my side. That did not work out so well. Bending over and twisting around made it come loose. I reserve my stomach for my pump sites. I don’t see how putting a garter over would smooth it out any, but you could try. To me, the benefits far outweigh the “lump”. Your sides could be a good place to try that might not be as noticeable. That would not work for me because I’m a side sleeper. I have adjusted to being aware of the sensor when changing clothes or going to the restroom or having sex with my husband. It doesn’t get in the way, but I do try to be careful not to rip it out. I put liquid skintac on the sensor adhesive patch to help it stick. That works well. I love my dexcom cgm!

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