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How Much Insulin Is Too Much At One Injection

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Insulin Poisoning With Suicidal Intent

Go to: A 27-year-old paramedical personnel without any comorbidities, working as an assistant in the operation theater, was found to be drowsy and drenched in sweat with bradycardia (34 beats/min) and hypotension (80/50 mm of Hg). She was immediately shifted to ICU. She was pale and there was no cyanosis, icterus, clubbing, lymphadenopathy, or any evidence of external injury. Temperature was 99.0°F, with a respiratory rate of 20/min and cold peripheries. Pupils were bilateral 3 mm, reactive to light, and oculocephalic reflex was preserved. Deep tendon reflexes were brisk and plantars were flexor. Meningeal signs were absent. Her systemic examination was unremarkable. An electrocardiogram showed sinus bradycardia. Atropine was given intravenously and normal saline infusion started. Blood pressure remained low which prompted initiation of norepinephrine drip. Capillary blood glucose (CBG) was 35 mg/dL, hence 50 mL of 50% dextrose bolus was given and 5% dextrose infusion started. Her neurological status started deteriorating and she rapidly lapsed into coma, 90 minutes from her initial presentation. At this stage, pupils were bilateral 2 mm and nonreactive, with loss of occulocephali Continue reading >>

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Popular Questions

  1. CalgaryDiabetic

    Yes with that much insulin it is very difficult if not impossible to loose tummy grease. However our Lloyd has done it. If you cut the calories you will loose muscle mass even with prodigious amounts of exercise.

  2. MarkM

    Originally Posted by KatieCippriano
    ... every time a doctor sees how much insulin I'm on, they comment about the amount. Also, I almost cannot lose thirty-five pounds that need to go. I was curious if the amount of insulin affected that. ... One of the effects of insulin is that it inhibits the burning of fat. So injecting a large amount of it makes losing weight difficult. You need to inject as much insulin as it takes to keep blood sugar down. But high insulin levels are not good. They are associated with increased risk of heart disease and cancer. Injecting large amounts of insulin also makes insulin resistance even worse. So the more you can improve your insulin sensitivity through diet and exercise, the better.
    Welcome to the forum .

  3. KatieCippriano

    Thank you Lloyd, for the advice. For the past couple of days, I've been able to get by on a much smaller dose, around forty units am and pm. That's really carb restricted for me, so I'll have to see if I can stick to it.

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