DiabetesTalk.Net

How Are Insulin Shots Made

Share on facebook

Insulin And Type 2 Diabetes: What You Should Know

Insulin and Type 2 Diabetes If your health care provider offered you a medication to help you feel better and get your blood sugar under control, would you try it? If so, you might be ready to start taking insulin. Does insulin immediately make you think of type 1 diabetes? Think again. Between 30 and 40 percent of people with type 2 diabetes take insulin. In fact, there are more people with type 2 diabetes who take insulin than type 1 because of the much larger number of people with type 2. Experts believe even more people with type 2 should be taking insulin to control blood sugar -- and the earlier, the better. With an increase in people developing type 2 at a younger age and living longer, more and more people with type 2 will likely be taking insulin. "If you live long enough with type 2 diabetes, odds are good you'll eventually need insulin," says William Polonsky, Ph.D., CDE, associate clinical professor of psychiatry at the University of California, San Diego; founder and president of the Behavioral Diabetes Institute; and author of Diabetes Burnout: What to Do When You Can't Take It Anymore (American Diabetes Association, 1999). Producing Less Insulin Naturally Over Time R Continue reading >>

Share on facebook

Popular Questions

  1. Marzeater

    Not your own body produced. I mean the stuff given to inject yourself.
    I've been told it's from pigs. Is that true?

  2. cugila

    An extract:
    Where Does Commercial Insulin Come From?
    The first successful insulin preparations came from cows (and later pigs). The pancreatic islets and the insulin protein contained within them were isolated from animals slaughtered for food in a similar but more complex fashion than was used by our doctor and med-student duo. The bovine (cow) and porcine (pig) insulin were purified, bottled, and sold. Bovine and porcine insulin worked very well (and still do!) for the vast majority of patients, but some could develop an allergy or other types of reactions to the foreign protein (a foreign protein is a protein which is not native to humans). In the 1980's technology had advanced to the point where we could make human insulin. The advantage would be that human insulin would have a much lower chance of inducing a reaction because it is not a foreign protein (all humans have the exact same insulin, so we do not "see" this as a foreign protein). The technology which made this approach possible was the development of recombinant DNA techniques. In simple terms, the human gene which codes for the insulin protein was cloned (copied) and then put inside of bacteria. A number of tricks were performed on this gene to make the bacteria want to use it to constantly make insulin. Big vats of bacteria now make tons of human insulin. From this, pharmaceutical companies can isolate pure human insulin.
    The full article here.
    http://www.endocrineweb.com/diabetes/2insulin.html

  3. kewgirl

    Hi Marzeater
    There are currently 3 Types of Insulin available in the UK. Then within each type there are a variety of insulin’s, which differ in the way they act and/or how long they last.
    Animal Insulin
    Human Synthetic Insulin
    Genetically Modified (GM) Synthetic Analogues.
    Animal insulin is extracted from the pancreases of dead pigs (Porcine Insulin) and cattle (Bovine / Beef Insulin). Following extraction they are highly purified. Animal insulin is the oldest type of insulin in use.
    However……in the 1920’s to overcome the shortage of beef insulin whale (as in the large mammals that swim in the sea not the country) insulin was also manufactured. :shock:
    Examples in use today: Hypurin Porcine & Bovine Insulin, Hypurin Bovine Lente & Hypurin Bovine Protamine Zinc Insulin (PZI).
    Human Synthetic Insulin is not extracted from dead humans!
    It is made in the laboratory using recombinant DNA technology based on the DNA structure of insulin that human pancreases secrete.
    Human insulin is grown in the lab inside common bacteria. The bacteria Escherichia coli or E-Coli is by far the most widely used type of bacterium, but yeast cells are also used.
    Human synthetic insulin was developed to make insulin more available world wide.
    There were concerns that the supply for insulin globally would outstrip the supply of animal insulin, which has in fact not happened.
    Examples in use today: Actrapid, Humalin I, Insulatard, Insuman
    GM Synthetic Analogues
    The newest kids on the block! Manufactured in the laboratory by modifying the chemical structure of human synthetic insulin so that the resulting compound has different chemical properties to human synthetic insulin. Insulin analogues are therefore man made or artificial products cultivated from deactivated e-coli or bakers yeast cells.
    Examples in use today: Apidra, Novorapid, Humalog, Lantus, Levemir
    Insulin is like a string of beads and the way in which the beads are linked together and more significantly how they come apart denotes the mode of action for each of the respective types thus some insulin’s begin acting very quickly after injecting and other insulin’s take longer to work.
    Some insulin are combined so the short acting & the longer acting component of the insulin are mixed together such as Novomix (analogue), Humalog Mix (analogue), Mixtard (human), Humalin M3 (human), Porcine 30/70 mix (animal).
    Human synthetic insulin & GM analogues have differences in their amino acid structure whilst animal insulin has the nearest amino acid structure to human (non synthetic) insulin.
    Txx

  4. -> Continue reading
read more close

Related Articles

  • How Are Insulin Shots Made

    What is insulin? Insulin is a hormone made by an organ located behind the stomach called the pancreas. Here, insulin is released into the bloodstream by specialised cells called beta cells found in areas of the pancreas called islets of langerhans (the term insulin comes from the Latin insula meaning island). Insulin can also be given as a medicine for patients with diabetes because they do not make enough of their own. It is usually given in the ...

    insulin Dec 30, 2017
  • Which Diabetes Needs Insulin Shots

    A friend recently told me that she always comes up with the perfect comeback. Her problem is that she thinks of it 20 minutes too late. Yep, sometimes timing is everything. When it comes to diabetes care of our pets, timing can make the difference between a well regulated diabetic pet and a “mostly” regulated diabetic pet. Routines may not be exciting, but routines make for a well-regulated diabetic pet! After two plus decades practicing vete ...

    insulin Jan 2, 2018
  • Which Diabetes Requires Insulin Shots

    Here are eight of the most common chronic conditions we treat in veterinary practice. 7% (per patient per month) from 2008 to 2009. Depression. Type 1 diabetes is an autoimmune disease that results in destruction of the insulin producing cells. "Autoimmune Disease Treatment With New Injection. Blood Clots Heparin or Lovenox Injections Hemophilia (Factor VIII deficiency). High Blood Pressure There are numerous drugs commonly prescribed for patient ...

    insulin Jan 12, 2018
  • Do Insulin Shots Hurt Gestational Diabetes

    This pregnancy complication is more common than you might think. Learn who's at risk for it, how it's detected, and what can be done to treat it. For years, doctors believed that gestational diabetes affected three to five percent of all pregnancies, but new, more rigorous diagnostic criteria puts the number closer to 18 percent. The condition, which can strike any pregnant woman, usually develops in the second trimester, between weeks 24 and 28, ...

    insulin Dec 31, 2017
  • Where Insulin Shots Are Given

    Go to site For Pet Owners Good glycemic control is dependent upon a controlled and consistent dietary intake. It is important to achieve and then maintain a normal body weight, because this is a strong indicator of good diabetic control. The dietary requirements of a diabetic dog are highly variable—diet must be individually tailored for each dog. Body weight is a major factor in diet selections. Obese dogs require reduced caloric intake, eithe ...

    insulin Dec 30, 2017
  • Do Insulin Shots Hurt

    If you have Type 2 diabetes, sooner or later you may require insulin injections, either temporarily (as during infections) or permanently. This is nothing to be afraid of, even though many people with long-standing Type 2 diabetes literally spend years worrying about it. I usually teach all my patients how to inject themselves at our first or second meeting, before there’s any urgency. Once they give themselves a sample injection of sterile sal ...

    insulin Dec 29, 2017

Popular Articles

More in insulin