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Does Insulin Lower Blood Glucose

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Prediabetes & Insulin Resistance

What is insulin? Insulin is a hormone made in the pancreas, an organ located behind the stomach. The pancreas contains clusters of cells called islets. Beta cells within the islets make insulin and release it into the blood. Insulin plays a major role in metabolism—the way the body uses digested food for energy. The digestive tract breaks down carbohydrates—sugars and starches found in many foods—into glucose. Glucose is a form of sugar that enters the bloodstream. With the help of insulin, cells throughout the body absorb glucose and use it for energy. Insulin's Role in Blood Glucose Control When blood glucose levels rise after a meal, the pancreas releases insulin into the blood. Insulin and glucose then travel in the blood to cells throughout the body. Insulin helps muscle, fat, and liver cells absorb glucose from the bloodstream, lowering blood glucose levels. Insulin stimulates the liver and muscle tissue to store excess glucose. The stored form of glucose is called glycogen. Insulin also lowers blood glucose levels by reducing glucose production in the liver. In a healthy person, these functions allow blood glucose and insulin levels to remain in the normal range. What Continue reading >>

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Popular Questions

  1. Lukose Thampy

    generally speaking, the insulin hormone will bind to receptors on cells it encounters and induce increased expression of glucose channels on the plasma membrane of the cell; this physically enables glucose to leave the blood/interstitium and enter the cell, causing blood glucose levels to fall.

  2. Michael L. Jirka

    You need Insulin as a transporter across the cellular membrane to get glucose into the cell where it is needed.
    You need Cytochrome C to get oxygen across the cellular membrane to get oxygen to where it is needed. If your furnace if faulty, you breath Carbon Monoxide that binds with Cytochrome C and oxygen builds up in your blood … but can’t get to the cells where it is needed.
    Similarly, if there is no insulin in the blood, GLUCOSE builds up in the blood stream but can’t get into the cell where it is needed. The cells are forced to use fats and proteins that don’t burn cleanly (like smokey diesel fuel). Byproducts build up in the blood and can kill you … and you have all this glucose just waiting to be delivered but the truckers are on strike.

    With Cytochrome C and Insulin, you have all the makins to make a clean burning fire … I’ll bring the hot dogs.

  3. Johanna Kristin Ellerup

    The simplest laymens explanation is direct - When you see and smell food your body starts to produce enzyme enriched saliva designed to chemically coat and start the metabolic process of digestion. This also signals the release of substances in the stomach (pepsin for one) and the colon in preparation. There are two key players in the maintenance of blood sugar levels - cortisol and insulin (there are others that signal the release and inhibition of these as well). The main function of cortisol is to keep blood glucose circulating or stored in a quickly convertible form so that it is always readily available for use as the body needs it in times of fasting. Insulin is secreted by the Islet of Langerhans cells in response to elevated blood glucose to take it out of the blood stream and increase its absorption by organs and tissues. Glucose and water are an energy (food) source requirement for all metabolic processes, where it gets converted to other forms, like glycogen which is the main component in the brain. Our body is even designed, during times of fasting, to convert proteins into glucose via gluconeogenesis, with substances like ketones as the by-product.
    This process is quite fascinating and more complex than explained here, with intricate signally pathways and digestive enzymes as key figures. When a person has type 1 (usually diagnosed in early childhood as non-functioning pancreatic Beta cells) or type 2 (normally diagnosed later due to stress or other pancreatic dysfunction), the role of endogenous insulin (types 1 & 2) and insulin secretogues (type 2) are vital because excess glucose accumulates in the blood stream causing a hyper-osmotic like state (causing other diseases like peripheral artery occlusion, fungal infections, etc) yet their organs and tissues are being deprived of energy.
    Hope this explanation helps!

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