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Can Type 1 Diabetes Be Reversed With Diet?

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Fasting Diet May Help Regenerate A Diabetic Pancreas

"The pancreas can be triggered to regenerate itself through a type of fasting diet, say US researchers," BBC News reports. Research in mice found a low-calorie diet may help in cases of type 1 and type 2 diabetes. The pancreas is an organ that uses specialised cells known as beta cells to produce the hormone insulin, which the body uses to break down sugars in the blood (glucose). In type 1 diabetes the pancreas stops producing insulin. In type 2 diabetes either not enough insulin is produced or cells in the body fail to respond to insulin (insulin resistance). Mice were fed for four days on a low-calorie, low-protein and low-carbohydrate but high-fat diet, receiving half their normal daily calorie intake on day one, followed by three days of 10% of their normal calorie intake. Researchers repeated this fast on three occasions, with 10 days of refeeding in between. They then examined the pancreas. They found in mice modelled to have both type 1 and type 2 diabetes, insulin production was restored, insulin resistance was reduced, and beta cells could be regenerated. Early lab study involving human cell samples showed similar potential. These are promising results, but further studie Continue reading >>

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Popular Questions

  1. utshell

    I've been nervous to post this, but I'm just going to throw this out there...does anyone use Metformin to "optimize" insulin and (potentially) weight loss? All current signs point that I'm one of those women Dr. Gerber described in the last podcast - insulin sensitive, lab work excellent, but just hold onto weight and difficulty losing it. Insulin test is pending - that said, my A1C has been excellent for years so my provider expects my insulin to be good, but maybe not optimal.
    I do strict keto, IF, and up to 72 hour fasting. My latest stall is at 6 weeks.

    Thoughts? I know using medication to basically optimize could be controversial. (And berberine hasn't done anything.)

  2. Cocoplum

    I take 1000 mg per day of metformin, up from 500 mg last year. My primary care physician was totally cool with writing the prescription when I asked. My goals were a wide range of health benefits; my weight after 2.5 years in ketosis is great (same as freshman year college), and my HA1c is 5.0, so weight loss wasn't my goal. A great survey paper on metformin is available (free full text) here:
    www.cell.com/cell-metabolism/pdf/S1550-4131(16)30229-7.pdf
    90
    All the best,

    Kevin

  3. utshell

    Thanks! I've read quite a few LCHF researchers/experts take it and aren't necessarily diabetic. I'm not sure if that's true or not. I figured it won't hurt anything. My A1C fluctuates between 5-5.2, and has been as low as 4.9. But I still carry a bit of excess weight that even on strict keto and fasting is very slow to come off and has stalled for over 6 weeks now. I figure really working on the insulin level can't hurt the situation I can't find literature on this application specifically and was curious if anyone here has had any experience with this.

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