Why Is Diabetes Genetic?

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Genetics Of Type 1a

Type 1 diabetes is a complex genetic disorder. There are now at least 20 insulin-dependent genes associated with the development of diabetes. Type 1 diabetes is a complex genetic disorder. It occurs more frequently in families in which there are other relatives with type 1 diabetes and other autoimmune conditions. Children have a 5% to 6% chance of developing diabetes if their father has type 1 diabetes, and a 3% to 4% chance if their mother has type 1 diabetes. It is thought that some of the mother’s chromosomal material, or DNA, gets inactivated when passed on to the child, thereby accounting for the difference in the children’s diabetes risk. If a sibling has type 1 diabetes, the risk is 5-6%; however, if the sibling has identical MHC (Major Histocompatibility Complex) haplotypes, the risk increases. When one identical twin has diabetes, the risk of the other twin developing diabetes traditionally has been thought to be about 40%. Recent research suggests that the number may be much higher. A number of genes have been identified that are associated with the development of diabetes. The chromosomal locations of these “diabetes genes” are called inherited susceptibility lo Continue reading >>

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Popular Questions

  1. jamichristine


    I'm always on the verge of dehydration. Or.. i am dehydrated. I try and drink a lot of water, and i thought i did drink enough. I keep getting tired, dry skin, weird vision, head aches, and all those are a sign of it. Does anyone else get dehydrated frequently? If so, what do you do.. there has to be something else i can put into my diet to help me. Also, it being summer doesn't help one bit.. i'm always out in the sun. Is there any drink mix that i can put in water to help me become hydrated faster? Or powerade zero?
    gimmie some ideas please!!
    thank youu.

  2. vrocco1

    As far as I know, there is only one solution to dehydration, and that is drinking water. Adding supplements to your water won't prevent dehydration, but it does help you compensate for the effects caused by it. You should only add the supplements if you are sure you need them, since they can cause other problems.
    As a backpacker, I've learned that I can sometimes require one liter of water PER HOUR, in order to avoid dehydration. The key is to drink enough so that you remain on a "regular" schedule, and so that your "waste water" remains clear (there is not an easy way to say that ).

  3. Stump86

    If your BGs are high (I don't know if they are or not) getting them down (at least under about 180 or so) will really help you stop losing water due to your kidneys trying to remove glucose from your blood.
    Drinking lots of water, as Vern says, is the best solution to combat dehydration, but if your BGs are high you may be losing any extra water you take in just as easily. Clear urine is a good marker for drinking enough water if your BGs are in a good range, but if not, it can be clear and you can still be dehydrated simply because of the amount of water you are losing.

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