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Which Are Microvascular Complications Of Diabetes Mellitus

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Why Are People With Diabetes Prone To Developing Chronic Wounds?

Wound Healing in Diabetes The diabetic ulcer is an excellent example of how multiple physiologic and biochemical defects can lead to impaired wound healing. Fifteen percent of patients suffering from DM will suffer a foot ulcer in their lifetime[1]. Patients with DM show a 5-50 fold higher risk of non-traumatic amputation compared with non-diabetic individuals[2]. Nearly 50% of all non-traumatic lower extremity amputations performed in the US are due to DM[3]. The reasons for poor wound healing in DM are many and varied. Diabetic foot ulcers are often caused by repetitive mechanical stress, unrecognised by the patient because of peripheral neuropathy and loss of protective sensation. In addition, the presence of peripheral vascular disease and infection can lead to poor healing of foot wounds and to the development of gangrene. An acute wound in a diabetic patient or a constant and persistent level of trauma, may lead to the development of one of these troublesome wounds. Chronic wounds appear to become “stuck” in the inflammatory and proliferative phases of wound healing. This allows for repeated injury, infection and inflammation. All of this impairs full wound closure. There Continue reading >>

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  1. abijann

    An ultrasound, CT scan, or even an MRI...which are all film testing
    can give the doctor an idea of possible Cirrhosis. I will explain why.
    When the liver cells become damaged, the immune system of the
    body will respond to this and cause inflammation to develop inside
    the liver [This will cause the liver to enlarge in size and takes on
    a spongy texture].
    When the liver cells start to die off and form scar tissue inside
    the liver (mild scar tissue is known as fibrosis). The liver
    tries to regenerate new cells...but the scar tissue prevents
    the cells from connecting and it bunches up against this
    scar tissue and start to cause a knobby/lumpy texture.
    As more scar tissue forms in the liver from the cells
    dying off...the scar tissue will start to connect together.
    This acts like a wall. It changes the inside structure of
    the liver. The scar tissue starts to block the flow of
    blood going to the remaining liver cells and will
    eventually reach the point that the blood will no
    longer go through the liver and back to the heart.
    This is known as Cirrhosis of the liver. When
    Cirrhosis develops, the liver will start to shrink in size
    and take on a harder texture.
    So now you can tell what they may be seeing.
    A liver biopsy is an invasive test...if she doesn't want
    evaluated for liver transplantation or the doctors believe
    she may not live through the long hours of transplant
    surgery...then they probably don't want her to have to
    go through a test for this. She should be seeing either
    a gastroenterologist or hepatologist now.
    The fluid in her legs and feet is caused because
    Cirrhosis disease hold sodium inside the patient body...
    this holds onto the fluid. Patient are usually started on
    a "lower" sodium diet and given diuretics. However,
    sodium has to be checked on blood work...since it is
    one of the electrolytes that help the heart beat in rhythm.
    The fluid that builds up in the stomach area, is known as
    Ascites. The liver can no longer make a protein, Albumin,
    which hold fluid inside our vessels. The fluid leaks out
    an collects there. A procedure known as Paracentesis
    will help drain this fluid. It give patients instant relief.
    Confusion, disorientation, sleep pattern changes, hand
    tremors are caused by toxins, like ammonia, building up
    in the body. It goes pass the blood brain barrier and into
    the brain to cause this condition know as Encephalopathy.
    The doctor can start a patient on meds know as Lactulose
    and Xifaxan. If not taken, the patient will...in time...go into
    a coma.
    Any blood seen in the sputum, vomit, rectal area is a dire
    emergency. The doctors can go in a band these weak
    vessel that balloon outward and break open, known as
    Varies. These develop because the blood doesn't flow
    through the liver, it backs up into the portal vein and
    these varies and also into the spleen causing it to
    enlarge in size.
    If she isn't able to eat, then the doctor may tell you what
    supplements to give her to keep her energy level up.
    These are different drinks, like Ensure..Glycerna...but
    the doctor should decide which one based on her blood work.
    Only the doctors can tell by her tests results, how long she
    might have to live...an educated guess.
    People who have Cirrhosis can become easily bruised and
    bleed very easily, since the liver can no longer make clotting
    factors. Try to remove rugs or things she may stumble over.
    Good to install night lights unless a light is kept on at night.
    Here are a few links about Cirrhosis. The first one is easy
    to understand and has different pages to look at.
    You can click on any links that I posted here
    ***Medicine Net: http://www.medicinenet.com/cirrhosis/art...
    Wiki: http://en.wikipedia.org/wiki/Cirrhosis
    Medscape: http://emedicine.medscape.com/article/18...
    Acute Liver Failure..Medscape: http://emedicine.medscape.com/article/177354-overview
    If she doesn't want to be in the hospital anymore, the doctor may
    sign for her to have palliative care at home...known as Hospice.
    You could also check with the Area of the Aging in your area.
    They provide senior citizens with alot of support, help, and
    sometime personal needs and food.
    HOSPICE SERVICES: http://www.hospicenet.org/html/services.html
    AREA OF THE AGING: http://www.n4a.org/
    I hope this has been of some help to you. Best wishes

  2. Comment

    Skip ordering pizza and make one of those crusts at home: gluten-free special potato crust, a quinoa basil crust that's also gluten cost-free, or this low-carb cauliflower brown crust area.

  3. Comment

    Halfway through your mealtime, stop and drink some water and decide if you are really hungry for the rest or for anyone who is just eating it because it's with your plate.

  4. -> Continue reading
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