When Metformin Stops Working

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Has Your Phentermine Stopped Working?

Phentermine is known to be an extremely effective weight loss medication. However, for those taking phentermine, the effects and results can vary throughout their prescription, and many of our forum users report that they feel their phentermine has stopped working, sometimes just a week or two after first starting to take it. Here we examine how phentermine works, what can cause a reduction in its effects, and how to overcome these issues in order to achieve great phentermine results. How Phentermine Works Phentermine acts on the central nervous system to stimulate the release of neurotransmitters in our brain, including dopamine, epinephrine (adrenalin) and norepinephrine (noradrenalin). This causes phentermine to increase alertness and energy levels, reduce hunger and minimize cravings. By helping to suppress appetite, phentermine encourages you to establish a healthier diet; with reduced cravings and less hunger, you will be able to concentrate on eating better and learning how to feel full while eating fewer calories by loading up on protein, fiber and lots of fruit and veg. Additionally, with the extra energy that phentermine gives due to its stimulant properties, you’ll fee Continue reading >>

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Popular Questions

  1. ColaJim

    Metformin: does it finally stop working for most people?

    Metformin: does it finally stop working for most people?
    in that i am now using using 4 500mg Metformin per day i would like to know if it's effects last forever or does it fade away like most medications.
    does using twice as much make it twice as effective?

  2. Shanny

    My metformin hasn't failed me yet, but I've been on it only 18 months. Pam has been on it for many years, if I'm not mistaken, and still trusts it.

  3. wallycorker

    I'm hoping that it will stop working for me soon. Why? Because I'm hoping to get off it altogether. I've been down from 2000mg to 1000mg per day for the last three months with hardly any difference in HbA1c - up only from 5.0% to 5.3%. I don't even know whether that slight change was due to the reduction in metformin or to something else.
    I've got an appointment with my doctor next Monday to review the situation. I'm hoping that he'll agree to a further reduction or - better still - a trial period with no metformin at all.
    Diet is the way to go for me!

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