What Is The Difference Between Diabetes Mellitus And Diabetes Insipidus?

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Diabetes Insipidus

Diabetes insipidus (DI) is a condition characterized by large amounts of dilute urine and increased thirst.[1] The amount of urine produced can be nearly 20 liters per day.[1] Reduction of fluid has little effect on the concentration of the urine.[1] Complications may include dehydration or seizures.[1] There are four types of DI, each with a different set of causes.[1] Central DI (CDI) is due to a lack of the hormone vasopressin (antidiuretic hormone).[1] This can be due to damage to the hypothalamus or pituitary gland or genetics.[1] Nephrogenic diabetes insipidus (NDI) occurs when the kidneys do not respond properly to vasopressin.[1] Dipsogenic DI is due to abnormal thirst mechanisms in the hypothalamus while gestational DI occurs only during pregnancy.[1] Diagnosis is often based on urine tests, blood tests, and the fluid deprivation test.[1] Diabetes mellitus is a separate condition with an unrelated mechanism, though both can result in the production of large amounts of urine.[1] Treatment involves drinking sufficient fluids to prevent dehydration.[1] Other treatments depend on the type.[1] In central and gestational disease treated is with desmopressin.[1] Nephrogenic disea Continue reading >>

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  1. Aruna kavitha

    Differentiate between Diabetes mellitus and Diabetes insipidus.

    Diabetes mellitus is a disorder of carbohydrate metabolism during which glucose in the body is not oxidised to produce energy. there is an accumulation of glucose in the blood due to less insulin production by beta cells of pancreas. The condition is called as hyperglycemia.The patient becomes weak as there is no production of energy. this abnormal metabolic condition results in fatigue and weight loss by the patient.
    Diabetes insipidus is the disorder caused due to less secretion of ADH (Anti Diuretic Hormone) by posterior pituitary gland. there is continuous loss of fluids of the body from the urine.

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