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What Are Side Effects Of Stopping Metformin?

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A Ci= Confidence Interval B Extended-release Metformin Was Clinically Similar To Immediate-release Metformin Based On The Pre-defined

Page 1 of 22 Metformin Hydrochloride Extended-Release Tablets 500 mg and 1000 mg Rx only DESCRIPTION Metformin hydrochloride extended-release tablets contain an oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin hydrochloride (N, N- dimethylimidodicarbonimidic diamide hydrochloride) is a member of the biguanide class of oral antihyperglycemics and is not chemically or pharmacologically related to any other class of oral antihyperglycemic agents. The empirical formula of metformin hydrochloride is C4H11N5•HCl and its molecular weight is 165.63. Its structural formula is: Metformin hydrochloride is a white to off-white crystalline powder that is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride is 6.68. Metformin hydrochloride extended-release tablets are designed for once-a-day oral administration and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the active ingredient metformin hydrochloride, each tablet contains the following inactive ingredients: ammonio methacrylate copolymer type A, ammonio metha Continue reading >>

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  1. tiktok2

    I was on 500 mg Metformin ER since Sept 2013. Never seemed to do much, but I figured it wasn't hurting anything to take it.
    It did cause my stomach to be a little flip-floppy if I was hungry for about 3 months, then that settled down.
    Was taking 2 500 mg pills but spaced out, one at dinner, one at bedtime, but not every night if I fell asleep before I took my pill.
    But that too didn't seem to be doing much, so my GP and I decided that I should try 3 500 mg pills.
    I was to take 2 at dinner and then 1 at lunch. I started with the 2 at dinner.
    But my stomach has been a "flip-floppy mess"; it took a few days for that to happen so I didn't realize that was what was happening;
    to the point that one night I swore I had tried to give myself food poisoning.
    But the more days I took the two, the worse it became.
    Its possible something else is going on, though I hope not, as that would be a worse scenario.
    So, tonight I took zero. I'll give it a day or two and then go back to 1. Then I'll go back to 2, but 12 hours apart.
    Then see if I can do 3, 8 hours apart.
    I never did the regular metformin. I started with the metformin ER, as I have an inflammatory arthritis that causes gastritis and inflamed bowel,
    though since I've eliminated the cow dairy that I was allergic / sensitive to, and have been on Humira for a few years,
    my stomach has been nearly perfect.
    But I've also learned in my lifetime that if something has the potential to mess with the GI tract, there is an excellent chance that it will mess with mine.
    I'd like to hear your experiences if you had challenges taking metformin ER, and if you found methods that worked bettter than other methods in taking it.
    I'm still optimistic that I can worked this out.

  2. ShirlAgn

    I only take the regular metformin, but always with food in my stomach. But, is there a chance you are getting the flu? I don't have it, but I hear this stomach flu is lasting quite awhile.

  3. living_laughing

    What is the max dosage for Metformin ER? I thought Met maxed out at 2500mg, but not sure about the ER varitey. Could it be the medicine at 3500mg is just too strong?
    If I thought the meds were making me sick, then I would be very cautious and back off them. Too much meds can cause just as many problems as too little. TikTok, I hope you will call your doc soon and tell him/her your symptoms since starting the new regimine and I hope you will find some relief soon.

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