Sudden Onset Of Diabetes In Previously Healthy Female.
Did your sister have an infection - flu or diarrhoea preceding the diabetes? It can as far back as 6 months precious. Some patients do not recover from the infection and develop immune disturbances which can trigger autoimmune diseases, especially if there is a lack of vitamin D. Even a simole traveller's diarrhoea can do this since GLP-1 is produced and released from the distal part of the small intestine. GLP-1 in turn regulates the apoptosis of pancreatic beta cell as well as the production of beta cells from stem cells. Pancreatic beta cells have a high turnover rate and if there is a lack of gastrin, GLP-1 or other incretins released from the L and K cell of the intestinal tract, production of new cell may be slower than the apoptotic rate. Any inflammation of infection will increase the beta cell destruction and result can be type 1 diabetes at any age. An easy way to check whether it is type one or two is to check the level of C-peptide. If this is very low it means insulin release from beta cells is low since one molecule of C-peptide is released with each molecule of insulin. If insulin level and C-peptide are high then there is a problem of insulin resistance ie. insulin Continue reading >>