Metformin Surgery Lactic Acidosis

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A Ci= Confidence Interval B Extended-release Metformin Was Clinically Similar To Immediate-release Metformin Based On The Pre-defined

Page 1 of 22 Metformin Hydrochloride Extended-Release Tablets 500 mg and 1000 mg Rx only DESCRIPTION Metformin hydrochloride extended-release tablets contain an oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin hydrochloride (N, N- dimethylimidodicarbonimidic diamide hydrochloride) is a member of the biguanide class of oral antihyperglycemics and is not chemically or pharmacologically related to any other class of oral antihyperglycemic agents. The empirical formula of metformin hydrochloride is C4H11N5•HCl and its molecular weight is 165.63. Its structural formula is: Metformin hydrochloride is a white to off-white crystalline powder that is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride is 6.68. Metformin hydrochloride extended-release tablets are designed for once-a-day oral administration and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the active ingredient metformin hydrochloride, each tablet contains the following inactive ingredients: ammonio methacrylate copolymer type A, ammonio metha Continue reading >>

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Popular Questions

  1. Yahya Firoze

    This is what’s commonly referred to as Post-prandial Hypoglycemia.
    When you eat a heavy meal, especially one high in carbohydrates (pizza, pasta, etc), your gut is breaking down absorbing those carbohydrates into the bloodstream. This will increase the glucose content in your blood. Your pancreas detect all this glucose and decide to release Insulin. One of the reason for the release of insulin is so that the glucose can enter into your body cells (and thus your cells can use that glucose for much needed energy).
    When you eat a heavy carbohydrate meal (the best example being a heavy pizza meal), your pancreas can hypersecrete insulin into your bloodstream, which basically means your pancreas may release excessive insulin into the bloodstream. This increased amount of insulin can cause excessive glucose to leave your bloodstream and enter into your body cells. Therefore, that may leave your bloodstream low on glucose and thus you have what is known as Post-prandial hypoglycemia. This will cause you to feel sleepy (although it isnt the only mechanism in your body that causes you to feel sleepy after a heavy meal — ‘rest and digest’). Over time, the glucose and insulin levels in your blood will adjust on their own and you have absolutely nothing to worry about. (Also, note, this is by no means the ONLY physiological explanation for this phenomenon and it by no means absolutely negates the presence of any significant underlying pathology)

  2. Mahesh Kanniah

    No. Almost everyone feels sleepy after food caus the digestive process takes away the energy and you feel sleepy.
    What people do is either they change the food to something lighter and others cover it up with caffeine/nicotine.
    It's perfectly normal to feel sleepy after food. Just make sure you eat slowly and chew the food well enough and you should be good.
    Frequent urination and other symptoms determine if you are diabetic. Get your sugar levels checked.

  3. Ron Hunter

    Feeling sleepy after you eat could be the content of your food but it also could very well mean that you’re pre-diabetic. Right before I got full blown diabetes, if I ate something like pasta I would be so sleepy that I almost could not stay awake. Now one sign I use for having my blood sugar high is feeling sleepy after meals.

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