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Ketoacidosis Symptoms Non Diabetic

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Nondiabetic Ketoacidosis Caused By Severe Hyperthyroidism.

Abstract Severe hyperthyroidism is not included in the traditional differential diagnosis of ketoacidosis. However, thyroid hormone has well-documented lipolytic effects on adipocytes and may also promote hepatic beta-oxidation. We present a case in which a woman with severe hyperthyroidism developed otherwise unexplained ketoacidosis during the acute phase of her illness. We propose that thyrotoxicosis was a significant contributor to ketoacidosis in this patient and that severe hyperthyroidism should be added to the differential diagnosis of ketoacidosis. Continue reading >>

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  1. kris90

    Non Diabetic Ketoacidosis?

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  2. kris90

    I had been trying to correct what I believe to be small intestinal bacterial overgrowth (something I believe I have suffered from for years) with a ketogenic diet which has given me success in the past. My symptoms included: abdominal cramping/distention, bloating, gas (very foul), constipation, fatigue, and intense sugar cravings. I am otherwise very healthy (26 years old, 5'8 @ 160 lbs approx 8% bodyfat and active).
    This time around, I decided to follow a more strict ketogenic diet (one that is epi-paleo). I ate lots of salmon, mussels, grassfed beef, eggs, grass fed butter, coconut oil, occasional mixed nuts and almond butter. After a few days to a week in, I noticed more severe symptoms: nausea, racing heart, and spiking random fevers with chills after eating and worsening constipation & bloating let alone major headaches. I ended up checking in to the ER, and was given lactulose to help with constipation. It worked, and my bloating was gone, but still didn't feel right. I went back for some bloodwork, and everything came back normal (I can post results) blood glucose was 4.5 mmol/L. I noticed I would feel ok if I fasted, but as soon as I ate the high-fat keto meal, within an hour I'd spike a fever, and get major nausea and chills. I literally felt poisoned. I decided to check my urinary ketone levels using ketostix, and came back around 8 mmol/L. I was a little concerned given that on the pamphlet that a doctor should be contacted with a reading over 4 mmol/L. I thought perhaps my ketones were too high, so I decided to take in around 50g of carbs to see if that would bring me down. Bad idea. Nausea hit harder than ever and I was over the toilet thought I was dying (everything spinning, vision was fading out, body went numb and tingly, I was slowly drifting away). I had to get my wife to call 911, and luckily before they arrived, I snapped out of it, but had a mild fever and sweats and was shooken up.
    Paramedics said everything was fine, blood pressure a little high but normal with the stress. Also blood glucose was at 8 mmol/L. Decided to have them take me in. Had ketones checked at hospital and read 6 mmol/L, and blood glucose went up to 8.2 mmol/L. They monitored me for a few hours, and blood glucose dropped back to normal by early morning (4.0 mmol/L) and ketones slowly fell as well.
    The next day, I consumed a well balanced diet with carbs (avoiding refined/sugary carbs) and brought myself out of ketosis. All my symptoms went away and I felt better (other than feeling exhausted). Now today (a day later) I continued the well balanced diet, only now all my "pre-keto" symptoms reappeared (major foul gas, bloating, and constipation).
    Can anyone make any sense of this madness? Was this maybe a bad case of "die-off" symptoms? Or could my ketone level have caused me to feel "poisoned"? I wonder why my levels climbed so high since I am not a diabetic. I found a case of "non-diabetic ketoacidosis" which describes my case almost identically: http://www.empr.com/case-studies/a-...betic-patient-whats-the-cause/article/443559/
    Need suggestions on how to combat these GI issues/bacterial overgrowth now. Perhaps a non-keto/low carb diet (100g per day)?

  3. Jenelle

    I have had great success with a low-FODMAP approach. When I eliminate most of the foods that are high in FODMAPs, I experience almost zero digestive distress. If you haven't heard of this ~ definitely worth a Google.

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