How To Activate Beta Cells Of Pancreas

Share on facebook

Beta Cell Dysfunction And Insulin Resistance

Go to: Abstract Beta cell dysfunction and insulin resistance are inherently complex with their interrelation for triggering the pathogenesis of diabetes also somewhat undefined. Both pathogenic states induce hyperglycemia and therefore increase insulin demand. Beta cell dysfunction results from inadequate glucose sensing to stimulate insulin secretion therefore elevated glucose concentrations prevail. Persistently elevated glucose concentrations above the physiological range result in the manifestation of hyperglycemia. With systemic insulin resistance, insulin signaling within glucose recipient tissues is defective therefore hyperglycemia perseveres. Beta cell dysfunction supersedes insulin resistance in inducing diabetes. Both pathological states influence each other and presumably synergistically exacerbate diabetes. Preserving beta cell function and insulin signaling in beta cells and insulin signaling in the glucose recipient tissues will maintain glucose homeostasis. Keywords: beta cell compensation, diabetes, obesity, oxidative stress, proliferation Go to: Introduction Both beta cell dysfunction and insulin resistance lead to persistent hyperglycemia which characterizes type Continue reading >>

Share on facebook

Popular Questions

  1. mysterynana

    Fingers or Legs Cramping Hours after taking Insulin

    This is more of a question than discussion. Has anyone else got cramps after taking insulin, I take Lanus and Novolog. I asked my endro doctor and primary doctor and they both said they never heard of it. This is really bothering me, and I want to know is it rue or my imagination. Have a Blessed day.

  2. Mumbo7879

    I might start to ride the same rollercoaster of pain as ur self bro . Doesnt matter if too much high glucose sugar levels or too much low . As soon as we take insulin we scream out of pain . Huhhh big problem man . But i think the solution to that is first eating a lot like stomach full . And then injecting insulin in thighs . That way i never get cramps again . Common sense we get cramps when we inject insulin on empty or almost empty stomach thus insulin acts rapidly and sharply causing blood glucose to go down n that pressure of blood glucose going down disturbs our muscles . There for even if we take fast acting insulin or slow insulin through my experience . I say eat the hell out ur refregirator before taking insulin . Till u feel the food is gonna come out of u through ur mouth . Then inject insilin in thighs . That way the insulin even if fast acting acts slow through thighs . Never mix two insulin brands together at same time . Inject one . Then wait for an hour inject another one . Water . Yes . Drink a lot specially at night . And try to control ur self . At least if not much for two days . That way we can keep insulin far from us n give our body a break from insulin. The more the need for insulin the more muscle cramps . Please dont eat sweets u can lie to us all but stop lying to ur self . Vegies taste bad . Fruits get boring . It may be painful for ur mind to stop ur self from sweets n such non healthy meals n fastfoods . But . Is it a big price to pay to live longer ? Please keep that question in ur mind until ur last breath . Keep the need of insulin to minimum as possible . And i know those who have muscle cramps r the ones who lost lots of weight n r extremly thin . N then the muscle cramps just go to tell u n let u know that stop making it more thin than it already is . Gain wieght by eating natural things . Find something on internet that helps gain weight . Gain about 10 kg . Or 15kg after that just keep it that way so that ur muscles can tolerate n keep up with the speed and sharpness of insulin. No doctor told me this . But believe me . Iam never wrong .

  3. msann

    hey all i dont have cramps with my insulin lantus at night been taking for 17 years i take 22 units at night 8 in the morning you might have some other problems good luck

  4. -> Continue reading
read more close

Related Articles

  • Pancreas Beta Cells

    The Harvard Stem Cell Institute (HSCI), three of Harvard's clinical affiliates, and a biopharmaceutical company have formed an unusual collaboration to establish the Boston Autologous Islet Replacement Program (BAIRT) to accelerate a cure for diabetes. Recent advancements in stem cell biology have provided an unprecedented opportunity to treat diabetes, researchers say. HSCI co-director Doug Melton has developed a process to generate virtually un ...

    diabetes Jan 6, 2018
  • Beta Cells In Pancreas

    Summary Planar cell polarity (PCP) refers to the collective orientation of cells within the epithelial plane. We show that progenitor cells forming the ducts of the embryonic pancreas express PCP proteins and exhibit an active PCP pathway. Planar polarity proteins are acquired at embryonic day 11.5 synchronously to apicobasal polarization of pancreas progenitors. Loss of function of the two PCP core components Celsr2 and Celsr3 shows that they co ...

    diabetes Jan 6, 2018
  • Beta Cells Of Pancreas

    An overwhelming amount of scientific evidence shows that a high-fat diet is the single most effective method at inducing insulin resistance in both your liver and muscle. This research clearly demonstrates that increasing dietary fat intake has an immediate negative effect on insulin sensitivity, which can then develop into a chronic state of insulin resistance and diabetes if the quantity of dietary fat remains high (1–26). For more informatio ...

    diabetes Feb 22, 2018
  • Insulin Beta Cells

    - [Voiceover] As you can see on this gentleman right here, he's got a liver, and then this organ down here is referred to as the pancreas. Now the pancreas sits in the retroperitoneum which relative to the liver, which sits in the peritoneum, or in the abdomen, the pancreas is found to the back and to the left, to the back and to the left. And what's distinctive about the pancreas is it's blood supply. And so we can go through that in a little mo ...

    insulin Feb 25, 2018
  • Diabetes Beta Cells

    Beta cells (β cells) are a type of cell found in the pancreatic islets of the pancreas. They make up 65-80% of the cells in the islets. Function[edit] The primary function of a beta cell is to store and release insulin. Insulin is a hormone that brings about effects which reduce blood glucose concentration. Beta cells can respond quickly to spikes in blood glucose concentrations by secreting some of their stored insulin while simultaneously prod ...

    diabetes Jan 6, 2018
  • Type 2 Diabetes Beta Cells

    If we could only get the beta cells in the pancreas to rejuvenate themselves, we could then cure diabetes. The problem also involves shutting off immune responses, and eliminating behavioral and environmental factors that precipitate diabetes. When there is an immune response that attacks beta cells, we have Type 1 diabetes. Over a fairly short period of time, it results in complete destruction of insulin-producing beta cells in the pancreas. If ...

    diabetes Feb 27, 2018

Popular Articles

More in diabetes

Whoops, looks like something went wrong.