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How Does Diabetes Cause Nephropathy

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Diagnosis And Treatment Of Diabetic Nephropathy In Type 1 And Type 2 Diabetes Patients

Zhenhua He* Washington University in St. Louis, Missouri, USA Citation: He Z (2016) Diagnosis and Treatment of Diabetic Nephropathy in Type 1 and Type 2 Diabetes Patients. J Mol Biomark Diagn 7:295. doi: 10.4172/2155-9929.1000295 Copyright: © 2016 He Z. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Visit for more related articles at Journal of Molecular Biomarkers & Diagnosis Abstract Diabetic nephropathy (DN) is the leading cause of end-stage renal disease and the care of patients with diabetes and DN contributes significantly to health care costs. Of patients with type 1 diabetes, approx 20%-30% will eventually develop DN, whereas about 10%-20% of those with type 2 diabetes will do so. In the past couple of decades, there have been notable advances in our knowledge regarding the DN, including the advent of interventions that can significantly slow or even reverse the course of progressive disease. This review describes the definition and detection of diabetic kidney disease, its natural histo Continue reading >>

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  1. Steve Rapaport

    These conditions (diabetic retinopathy and diabetic neuropathy) are the direct results of long-standing persistent hyperglycemia (high blood sugar). This is not a controversial statement.
    The progression of these conditions can be stopped, but only by removing the cause. The person must absolutely stop allowing high blood sugar to exist, which will require purchase of a glucometer, and a period (perhaps months) of persistent blood sugar testing before and after meals, and adjustments in diet and insulin dosage, to prevent post-meal blood sugar ever going above 140 mg/dl (7.7 mmol/L). Ever. Each time blood sugar goes above that level, a bit more damage will result to the eyes and feet. (This is a controversial statement, but the many studies at the link below will back me up.)
    Once the patient is very familiar with the diet, insulin dosage and exercise levels that will keep blood sugar under this level at all times, they might reduce the amount of testing but keep the diet and insulin habits intact. If the patient is not currently injecting insulin, it is time for them to discuss that possibility with their doctor, since the current medications they are taking are not providing adequate hyperglycemia control.
    Further details can be found (along with studies showing why these levels are important) at the well-known diabetic site I keep recommending, phlaunt.com: Do People with Type 2 Always Deteriorate?

    I have no connection to that site other than being very impressed by Jenny Ruhl's research and writing. She's never heard of me.

  2. Edwin Ek

    Here comes the unexpected part: fat paralyzes insulin and sugar makes insulin work better. This has been known since the 1930's (results published in respected medical journals), yet everybody knows you should eat a low-carbohydrate high-fat diet if you have diabetes to keep your blood sugar under control. In fact, that is the exact opposite of the proper advice (not the blood-sugar part, but the diet part). No wonder people with type-2 diabetes under standard care never get better.

  3. Michael Edun

    People having type 2 diabetes such symptoms such as losing sight and painful feet should need to take high organic fibre supplements which help to reduce excess sugar from the blood stream which can cause blur vision first and later leading to blindness.. If you are to one having such or you know someone having such.. Click >>> Evergreen Health Care Supplements to learn more on what diabetes is about, be it type 1 or 2, symptoms and organic natural remedy supplements can help to reduce the signs

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