Diabetic Ketoacidosis Pathophysiology Ppt

Share on facebook

Diabetic Ketoacidiosis

Objectives Introduction and awareness of the pathophysiology of Diabetic Ketoacidosis Clinical recognition,establishing a diagnosis and assessment of co-morbidities Clinical Management of DKA and recognition of complications Introduction: State of absolute or relative insulin deficiency aggravated by ensuing hyperglycemia, dehydration, and acidosis-producing derangements in intermediary metabolism. Characterized by Hyperglycemia over 300 mg/dL Low bicarbonate (<15 mEq/L) Acidosis (pH <7.30) Ketonemia and ketonuria. Path physiology Insulin deficiency Increased counter-regulatory hormones (ie, glucagon, cortisol, growth hormone, epinephrine). Enhanced hepatic gluconeogenesis, glycogenolysis, and lipolysis Osmolality Measured as 2(Na+) (mEq/L) + glucose (mg/dL)/18 + BUN(mg/dL)/2.8. Patients with DKA who are in a coma typically have osmolalities >330 mOsm/kg H20. If the osmolality is less than this in a comatose patient, search for another cause of obtundation. Repeat labs are critical Potassium needs to be checked every 1-2 hours during initial treatment. Glucose and other electrolytes should be checked every 2 hours or so during initial aggressive volume, glucose, and electrolyte man Continue reading >>

Share on facebook

Popular Questions

  1. lia

    Anyone use the A1C at home test kits?

    I tried doing the forum search, but a1c is too short to be included in it, so the results were all about 'home.' Nothing about a1c.
    I was just looking into them and Walmart has the Relion a1c home test kit for $9. Compared to $85 at the doctors, they are going to be losing my business.
    Most of them take about a week to give you the results. You have to mail the test in, and they mail or email the results back. Bayer has one that is completely at home and it just takes a few minutes, but it is close to $30.
    They are supposed to be as accurate as the ones sent to the lab from the blood sample people. Amazon is out of them right now, but the comments are still up for them, and one person got the exact same result from it that he did from the doctor's lab.
    That's nice to be able to do. Things are looking up. Go science, go

  2. smorgan

    I've used the Wal-Mart one several times, the one you mail in. I have no reason to believe it is any less accurate than the ones my doctor sends to the lab.

  3. jwags

    I buy the Bayer A1c Now kits when they are on sale. They will usually be $19.99 on sale and you get 2 tests. You get results in 5 minutes and they are pretty accurate. Check out the sale flyers for Walgreens, CVS, Drugmart.

  4. -> Continue reading
read more close

Related Articles

Popular Articles

More in diabetes