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Hba1c In Early Diabetic Pregnancy And Pregnancy Outcomes

A Danish population-based cohort study of 573 pregnancies in women with type 1 diabetes Abstract OBJECTIVE—To assess the association between first-trimester HbA1c (A1C) and the risk of adverse pregnancy outcomes in type 1 diabetic pregnancies. RESEARCH DESIGN AND METHODS—We identified all pregnant diabetic women in a Danish county from 1985 to 2003. A1C values from first trimester were collected, and pregnancy outcome was dichotomized as good (i.e., babies surviving the 1st month of life without major congenital abnormalities) and adverse (i.e., spontaneous and therapeutic abortion, stillbirth, neonatal death, or major congenital abnormalities detected within the 1st month). The prevalence of adverse outcomes was calculated according to quintiles of A1C. We computed receiver operating characteristic and lowess curve estimates and fitted logistic regression models to calculate prevalence odds ratio while adjusting for confounding by White class and smoking status. RESULTS—Of 573 pregnancies, 165 (29%) terminated with adverse outcomes. The prevalence of adverse outcomes varied sixfold from 12% (95% CI 7.2–17) in the lowest to 79% (60–91) in the highest quintile of A1C expos Continue reading >>

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Popular Questions

  1. st looney up the cream bun and jam

    I feel sure someone will ask, so: Though I have had the disease for 30 years, I am a well-controlled diabetic; my doctors proclaim themselves pleased with my tests, which I get done faithfully on schedule. Indeed, if I am bottoming out from time to time as I say, I am not in perfect control; I do make mistakes.

  2. I_pity_the_fool

    Drawing from personal experience of your problem, I'm inclined to think it might be because there's just so much of it. When I wake up after a midnight hypo I feel like I've been in a bath. If you've been lying in a hot bed for 5 hours sweating, I'm sure there's more chance for bacteria to fester a bit.
    As an aside - and I know this is kind of an obvious thing to ask - but have you ever tested your blood sugar when waking up from this. My nurse told me that there's a sort of a 'bounce' when the liver releases a whole load of sugar after you've been hypoglycemic for a while. I've been told to watch out for high blood sugar after a night-time hypo.

  3. TomMelee

    Oops that was a fail. Didn't mean to press "post." Feel free to delete that.
    Diabetic Ketoacidosis is what I meant to link to, and what you've got is the opposite. It's not uncommon for over-insulined folks to stink-ass.
    When you're insulin deficient, you smell sweet, somewhere between honeysuckle and acetone. When you've got too much, it's the opposite.

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