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What Happens To Glucose In The Liver?

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What Happens To Your Body When You Binge On Sugar

As mouth-watering as a sugar-laden sundae or icing-topped cupcake is, we should all know by now that sugar isn’t exactly healthy. In fact, it may be one of the worst things you can eat (that is, if you’re trying to live a long, healthy life). One study from UC San Francisco actually found that drinking sugary drinks like soda can age your body on a cellular level as quickly as cigarettes. The way the sweet stuff impacts your body is way more complex than just causing weight gain. In fact, when you eat a ton of sugar, almost every part of your body feels the strain—and that’s bad news for your health in both the short term and especially the long term. From an initial insulin spike to upping your chances of kidney failure down the road, this is what really happens in your body when you load up on sugar. Your brain responds to sugar the same way it would to cocaine. Eating sugar creates a surge of feel-good brain chemicals dopamine and serotonin. So does using certain drugs, like cocaine. And just like a drug, your body craves more after the initial high. “You then become addicted to that feeling, so every time you eat it you want to eat more,” explains Gina Sam, M.D., M. Continue reading >>

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    What happens to glucose in the liver?

    The liver does produce glucose in a way other than breaking down glycogen to glucose. Stored glycogen can barely cover for a day the glucose needs of a person that is fasting or on a strict diet.
    The more important process is gluconeogenesis in which the following molecules are used to produce glucose:
    1. lactate produced during anaerobic respiration in the skeletal muscles
    2.pyruvate after transamination to alanine
    3. all amino acids except (leucine and lysine) which can be converted to Kreb cycle intermediates ending up at the end of the cycle as oxaloacetate which can then be converted to pyruvate.
    4. glycerol (originating from fatty acids) after phosphorylation to glycerol-3-phosphate.
    Gluconeogenesis from these 3 or 4 carbon precursors is in effect a reversal of glycolysis. Only three stages of glycolysis that involve a high energy change and are thus irreversible are bypassed through a different route.
    These steps involve the enzymes glucose-6-phosphatase, fructose-1,6-bisphosphatase, and PEP carboxykinase instead of the corresponding glycolytic Hexokinase/glucokinase, phosphofructokinase, and pyruvate kinase enzymes.
    The liver stores glucose in the form of glycogen. Whenever you go for long periods of time without eating, the liver releases glucose into the blood stream to keep your blood sugar from going too low. If you eat too many carbohydrates, RHOC Recombinant Protein www.cusabio.com/protein-Recombinant_Prot... then the liver will store some and the rest will go to other places in your body, such as body fat. Believe it or not, the glucose can also be excreted into the urine too, so there are plenty of places for the glucose to go: liver, fat cells, muscles for energy, urine, etc...

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    For high blood glucose concentration>The pancreas will detect te high conc of glucose and stimulates the islets of langehan in the pancreas to secrete insulin. Insulin is brought to the liver by the blood, converting excess glucose into glycogen as storage in the liver and muscle cells. The excess glucose may also be converted to fats as storage.
    For low blood glucose conc> the islet of langerhan will be stimulated to produce glucagon. Glucagon in turn converts the stored glycogen to glucose that is available for use. This homeostatic control ensures that the blood glucose concentration is maintained as significant alterations in the conc may result in detrimental effects.
    High blood glucose conc that takes longer than usual to revert back to normal means the person is diabetic and glucose will be found in urine.
    On the other hand low blood glucose conc due to over secretion of insulin will lead to fainting spells, coma or even death.

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