What Causes The Blood Glucose Level To Increase In Liver Damage?
Chronic liver damage can result in the replacement of normal liver tissue with non-functioning scar tissue. Advanced liver damage is called cirrhosis, and glucose intolerance is a common feature of this condition. An article in the January 2009 issue of the “World Journal of Gastroenterology” reports that greater than 90 percent of people with liver cirrhosis are glucose intolerant, and nearly 30 percent will develop diabetes. Liver cirrhosis is irreversible and can be the result of alcoholic liver disease, hemochromatosis, non-alcoholic fatty liver disease or chronic hepatitis C infection. Video of the Day The liver is the primary disposal site of insulin; when the liver is damaged, less insulin is taken up and degraded, causing a condition of chronic hyperinsulinemia. A study in the July 1998 issue of “Hepatology” reports that hyperinsulinemia in patients with liver cirrhosis causes muscle insulin resistance. Another study in the March 1994 issue of “Hepatology” reports patients with cirrhosis exhibit metabolic abnormalities consistent with muscle tissue insulin resistance. This means that in people with impaired liver function, glucose is not as efficiently removed f Continue reading >>