106 Glucose Fasting

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Can Fasting Glucose Levels Or Post-breakfast Glucose Fluctuations Predict The Occurrence Of Nocturnal Asymptomatic Hypoglycemia In Type 1 Diabetic Patients Receiving Basal-bolus Insulin Therapy With Long-acting Insulin?

Abstract To investigate whether the occurrence of nocturnal asymptomatic hypoglycemia may be predicted based on fasting glucose levels and post-breakfast glucose fluctuations. The study subjects comprised type 1 diabetic patients who underwent CGM assessments and received basal-bolus insulin therapy with long-acting insulin. The subjects were evaluated for I) fasting glucose levels and II) the range of post-breakfast glucose elevation (from fasting glucose levels to postprandial 1- and 2-hour glucose levels). The patients were divided into those with asymptomatic hypoglycemia during nighttime and those without for comparison. Optimal cut-off values were also determined for relevant parameters that could predict nighttime hypoglycemia by using ROC analysis. Results 64 patients (mean HbA1c 8.7 ± 1.8%) were available for analysis. Nocturnal asymptomatic hypoglycemia occurred in 23 patients (35.9%). Fasting glucose levels (I) were significantly lower in those with hypoglycemia than those without (118 ± 35 mg/dL vs. 179 ± 65 mg/dL; P < 0.001). The range of post-breakfast glucose elevation (II) was significantly greater in those with hypoglycemia than in those without (postprandial 1- Continue reading >>

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Popular Questions

  1. denofhc

    I have been warned by my doctor that I may be headed toward diabetes because of my family history.
    I have tried to keep my weight under control. I exercise every day and watch what I eat.
    Never-the-less, I bought a glucose meter and was surprised to find that my fasting glucose reading is between 100 and 118 (average 109).
    I have redoubled my effort by almost totally eliminating sugar, white bread, potatoes, rice, etc. But the over 100 readings continue.
    Should I be concerned?

  2. ElkHunter

    I was told my doctor that a "normal" reading was between 90-105. ANYTHING, above and below that, you should be concerned with. I agree with what the doctor said, being just outside those numbers, you are stretching it.
    You say you watch what you eat. Seriously cut down on everything white. No Sugar, no white bread, nothing with white flower, no white rice, etc.
    Then, start looking at your carbs. Carbs equate to Sugar. I keep my carb intake to 100 carbs a day. Normal person can have 200 carbs a day. But, being diabetic, I'm not normal.
    You sound like you are off to a good start, but now you need to get serious about it. Get a book on carbs and start keeping track of carb intake. Start looking at diabetic cookbooks and what you can and cannot eat.
    You CAN improve what you are eating and reduce the numbers. You are not out of tolerance that far, but you are starting to get into a bad trend.
    Good luck.
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  3. SouthernBelleInUtah

    No alcohol. I was told to keep my carbs at 90 or less per day.

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